“印度版”抗癌药 "India edition"Anticancer drugs

　　价格约为正版药1/10 The price is about the original drug 1/10

　　今年67岁的周伯最近因为咳血住进了医院，一检查，是晚期肺癌。医生摇着头告诉家属：手术做不了了，癌细胞已经多处转移，病人身体状况差，不知能不能耐受放化疗。

This year 67 - year - old ZhouBo recently because the coughing up blood live in the hospital,A check,Advanced lung cancer is.The doctor shook his head told the patient's family:Surgery can't do the,The cancer has multiple metastases,The patient's body status difference,If I can withstand radiation and chemotherapy.

　　就在家属绝望之际，医生告诉他们，目前还有一种治疗手段可以尝试——靶向药物，但这些药每粒要五六百元，一天一粒，一个月下来就要一万多元。“我们都是普通的工薪族，这样的药哪里吃得起？”看着家属焦急无助的样子，医生意味深长地说：“你回家试试上网搜一下印度易瑞沙，自己想想办法吧。”

On the occasion of family despair,The doctor told them,At present, there are also a kind of treatment method can try - targeted drugs,But these medicine to every grain after yuan,One day a grain of,A month comes down to ten thousand yuan."We are all ordinary wage earner,This medicine where to eat up?"Look at family anxious helpless appearance,The doctor meaningfully said:"You home try Internet search India YiRui sand,His think of something."

　　周伯的儿子随后上网搜索，原来印度版抗癌药价格只是正版欧美药的1/10左右。如一种名为易瑞沙的肺癌靶向药物，正版一个月要1.5万多元，而“印度版”一个月才不到2000元。

ZhouBo son then Internet search,The original India edition anticancer drugs price only about 1/10 of the original Europe and the United States medicine.Such as a name YiRui sand of lung cancer targeted drugs,The original a month to 15000 yuan,and"India edition"A month to less than 2000 yuan.

　　

正版vs印度版 价差为何如此巨大？ The original price vs India edition why so great?

　　靶向抗癌药物是近年来颇受医学界推崇的癌症治疗方式，除了肺癌，目前乳腺癌、白血病、肠癌等都已有此类药物上市，其中以肺癌靶向药物易瑞沙、特罗凯和慢性髓性白血病治疗药物格列卫卖得最火。

Targeted cancer drugs in recent years is popular in the medical profession praise highly of cancer treatment,In addition to lung cancer,At present breast cancer/leukemia/Colorectal cancer, etc all have such drugs listed,The lung cancer targeted drugs YiRui sand/Special carleton ruthling and chronic myelogenous leukemia drugs gleevec sell the most fire.

　　据了解，这些抗癌药物目前在国内并没有生产，完全依靠从欧美医药公司进口。据一家正规国营药店的报价，易瑞沙每盒5400多元，一个月需3盒至少15000元；特罗凯每盒19800多元，一个月需服用一盒；格列卫每盒11500多元，一个月服2盒至少23000元。

It is understood,These cancer drugs currently in domestic and no production,Depend entirely on pharmaceutical companies from Europe and the United States imported.According to a normal state pharmacy offer,YiRui sand the magazine 5400 multivariate,A month to 3 box of at least 15000 yuan;Special carleton ruthling offers 19800 multivariate,A months need to take a box of;Gleevec offers 11500 multivariate,A month take 2 box of at least 23000 yuan.

　　相比之下，“印度版”抗癌药就便宜得多。印度第一大药业公司Natco生产的易瑞沙、特罗凯、格列卫等，价格大约是正版欧美药物的1/5~1/10。如“印度版”的易瑞沙，价格约为1800元一盒，特罗凯为4500元一盒，格列卫则为1800元一盒，且每盒均为30天的药量。

Compared with,"India edition"Anticancer drugs is much cheaper.India's first big pharmaceutical company Natco production YiRui sand/Special carleton ruthling/Gleevec, etc,The price is about the original drug 1/5 ~ 1/10 of Europe and America.if"India edition"YiRui of sand,The price is about 1800 yuan a box,Special carleton ruthling for 4500 yuan a box,Gleevec is for 1800 yuan a box,And the magazine are 30 days of dosage.

　　记者了解到，“印度版”药物之所以如此便宜，主要与印度的专利保护法律有关。某跨国制药企业市场部的一名主管透露，正版药物之所以贵，“首先是因为前期要投入巨大的研发成本，还要做大量的临床研究，这些成本最后都会被算进每一粒药片的价格中。再加上进口过程中涉及的税费，所以贵是有理由的。”也正因此，这些药物受到专利的保护，但在印度，却恰恰是个例外。

The reporter understands,"India edition"Drugs are so cheap,The main and India's patent protection law relevant.A multinational pharmaceutical enterprise marketing a competent revealed,The original drugs are expensive,"First, because the early to put huge r&d cost,Still need to do a lot of clinical research,These costs will be the last figure in every tablets in the price.Plus import process involved in taxes,So your is a reason."Are so,These drugs are patent protection,But in India,But just is an exception.

　　印度政府1970年通过的《印度专利法》只提供“工艺专利”，因此从1970年起，印度仿制药快速增长。直到2005年，印度才恢复了“药品专利”，但只针对1995年以后发明的新药或经改进后能大幅度提高疗效的药物。现在，一些印度药商依然一边生产仿制药，一边与欧美厂家进行专利法律战。再加上印度还有人力成本、资源等优势，所以原理几乎一样的药物，价格却有天壤之别。

The Indian government passed in 1970[Indian patent law]Only provide"Process patent",So since 1970,Indian generics rapid growth.Until 2005,India has just recovered"Drug patent",But only for 1995 years after the invention of new drugs or after the improvement can dramatically improve curative effect of the drug.now,Some Indian druggist still side production generics,Side with the European and American manufacturers patent legal battle.Plus India and human cost/Resources advantage,So principle almost the same drug,Prices are poles apart.

　　

销售链条：以网上代购为主 Sales chain:Online purchasing is given priority to

　　记者采访发现，“印度版”抗癌药的销售大多通过网络代购的形式进行，负责代购的主要是在印度工作的中国人，中间商贩基本都活跃在网络上，不与客户直接接触。

Reporters found that,"India edition"Anticancer drugs sales mostly through the form of network act as purchasing agency,Responsible for purchasing are mainly of the Chinese working in India,Intermediate vendors basic are active in the network,Not with direct contact with the customer.

　　记者在网上搜索到了不少代购网站。以某代购网站为例，上面展示了药物样品、价格及说明等，跟绝大部分同类型的药物代购网站一样，都没有“互联网药品经营许可证”，并没有在网上售药的资格。随后，记者联系上客服，对药的可靠性表示怀疑。客服则表示，药是从印度直接邮寄到中国的，网站会提供EMS国际快递单号、药房小票复印件、海关的检测证明票单等，保证是正品。

Reporter in the online search to many act as purchasing agency web site.Taking a act as purchasing agency web site as an example,It shows the drug samples/Price and so on,With most of the same type of drugs as well as act as purchasing agency web site,Are not"The Internet drug business license",And no online sale medicine qualification.then,Reporter contact customer service,The reliability of the drug to doubt.Customer service, said,Medicine from India direct mail to China,Website will provide EMS international express single number/Pharmacy copy slip/Customs check tickets, etc,Guarantee is the real thing.

　　而一些警觉性颇高的网站则表示只为患者及其直系亲属代购，并需要提供相关的医疗证明。有些网站还要求“出示三甲以上医院处方”。

And some watchfulness quite high web site, said only for patients and their immediate family act as purchasing agency,And need to provide the relevant medical proof.Some sites also requires"Show me more than 3 armour hospital prescription".

　　

印版抗癌药为何卖这么火？ Plate anticancer drugs why sell so fire?

　　医保虽可报销 但自付费用仍高 Although medical insurance can submit an expense account but out-of-pocket expenses is still high

　　采访中，不少肿瘤科医生一听“印度版”这几个字就讳莫如深，不愿多讲。一位再三叮嘱记者不能公开其姓名的肿瘤科教授向记者透露，据他所知，现在确实有不少病人在通过各种渠道购买“印度版”抗癌药，“我们作为医生，很难过问，更不能参与这种违法的事情。”不过这位教授承认，有时医生看见一些病人的经济实在非常困难，也会暗示病人自己去寻觅购买“印度版”药物的途径。

interview,A lot of oncology doctor a listen to"India edition"This a few words to keep secret,Don't want to speak more.A repeatedly told reporters can't open its name oncology department professor has revealed,According to his knowledge,Now do have a lot of patients in through various channels to buy"India edition"Anticancer drugs,"We as a doctor,Difficult to ask,More can't participate in this kind of illegal things."But the professor admit,Sometimes the doctor saw some patients economic was very difficult,Will also suggest that patients to seek to buy"India edition"Drug way.

　　据记者了解，现在有不少靶向药物都已纳入了医保报销范围，为何患者还要买“印度版”药物呢？对此，广州一家医院医务部门的主管分析说，巨大的价格差异造就了“印度版”药物的市场。

According to reporter understanding,Now there are a lot of targeted drugs have been included in the scope of medical insurance to submit an expense account,Why patients want to buy"India edition"Drug??this,Guangzhou hospital medical department supervisor analysis said,Huge price difference made"India edition"Drug market.

　　以广州医保为例，目前像易瑞沙、特罗凯和格列卫等药物，医保确实可以报销，但报销政策和报销比例有限制。像易瑞沙和特罗凯两种肺癌靶向药，就有适应症方面的规定，并非所有参保人都能获得报销：患者要先做一个基因测试，结果是阳性的患者才可以获得医保报销，而且报销费用满15000元就封顶不再报销。因此一些癌症晚期病人，各种治疗方式都已试过，基因检测不是阳性，正版药物又吃不起，本着“死马当活马医”的心态，就有可能会去购买“印度版”药物。

Medical insurance in guangzhou as an example,At present YiRui like sand/Special carleton ruthling and gleevec and drugs,Medical insurance really can submit an expense account,But to submit an expense account policies and submit an expense account scale restricted.Like YiRui sand and special carleton ruthling two kinds of lung cancer targeted drug,Have indications rules,Not all ginseng protect everyone can get to submit an expense account:Patients must do a genetic testing,The result is positive patients can get medical insurance to submit an expense account,And to submit an expense account cost nt $15000 is capped no longer to submit an expense account.So some terminal cancer patients,All kinds of treatments have been tried,Genetic testing is not positive,The original drug and leave,In line with"Die straws when"mentality,It is possible to buy"India edition"drug.

　　此外,按照医保政策，不同类型参保人的报销比例也有不同，目前的规定是：城镇职工医保在职者报销80%，退休者报销86%，而城镇居民医保则报销55%。照此计算，即使是报销比例最高的城镇职工医保退休病人，如果使用肺癌靶向药物易瑞沙，每月需要自付近3000元，如果是居民医保病人，则每月要自付8000多元。

In addition,According to the medical insurance policy,Different types of ginseng protect people also have different reimbursement ratio,The present regulation is:Town worker health incumbent to submit an expense account 80%,Retirees to submit an expense account 86%,And medical insurance for urban residents to submit an expense account is 55%.According to the calculation,Even the highest percentage of reimbursement of medical insurance for urban workers retired patients,If you use lung cancer targeted drugs YiRui sand,Monthly need pays nearly 3000 yuan,If it is residents health care patients,The monthly pay 8000 yuan since.

　　像主要用于治疗慢性髓性白血病的药物格列卫，服用正版药物每月药费超过2万元，即使能获得医保报销，患者每月自付的费用也达到4000~10000元。

Like is mainly used for the treatment of chronic myelogenous leukemia drugs gleevec,Taking the original drug monthly expenses for medicine more than 20000 yuan,Even if can obtain medical insurance to submit an expense account,Patients since the cost of pay every month has reached 4000 ~ 10000 yuan.

　　此外，靶向药大多只需口服，而且副作用比较轻，基本上是病人买了药回家自己吃就可以了，这一方便性也使得“印度版”药物有了生存的空间。

In addition,Targeted drug mostly just oral,And side effects are light,Basically is the patient bought medicine home you eat is ok,This convenience is also made"India edition"Drugs have the survival space.

　　

风险 risk

　　非法药物疗效没保障 Illegal drug curative effect not security

　　服药期间应监测随诊 During the medication should be monitoring follow-up

　　根据我国法律规定，这些看似便宜的印度版抗癌药物，由于没有相关的药物进口批文，运到国内出售属于走私行为，并被药监部门定性为假药。

According to China's laws and regulations,These seemingly cheap India version of anti-cancer drugs,Since there is no relevant drug import approval,To the domestic sale belongs to the act of smuggling,And was also department for qualitative fake.

　　据《人民日报》报道，深圳某知名企业派驻印度的员工何某，从2010年10月开始通过网络销售印度抗癌药物，通过邮寄、水客带过关等方式带到深圳，随后利用互联网联系国内买家，然后通过淘宝账号收取款项，并通知在国内的曾某、刘某通过物流公司给买家邮寄药品。2011年11月，公安机关将该3名犯罪嫌疑人抓获，缴获的药品经鉴定价值上百万元人民币。2012年5月，公安机关将该案移送深圳检察机关审查起诉。

According to[People's Daily]reports,Shenzhen a well-known enterprise in India HeMou employees,From October 2010 through the network sales India anti-cancer drugs,Through the mail/Water guest band pass, etc to shenzhen,Then use the Internet to contact the domestic buyers,Then through the clean out treasure collect payment account,And notice in the domestic CengMou/LiuMou through the logistics company to the buyer mailing drugs.In November 2011,The public security organ to the three suspects arrested,Captured drug classics appraisal value yuan.In May 2012,The public security organs will be transferred to the case of shenzhen procuratorial organs examine Sue.

　　事实上，“印度版”抗癌药的问题并不仅仅在于法律上，它们的疗效到底有没有保障，谁都没底。多名接受记者采访的三甲医院肿瘤科专家均不愿评价“印度版”药物的疗效，他们认为，由于无法掌握这些药的临床试验数据，别说疗效，就连安全性都不敢保证。近年来，他们已陆续碰到因为使用不正规药物而出现副作用的病人。

In fact,"India edition"Anticancer drugs problem lies not only in the law,Their curative effect exactly have security,Who are unavoidable.Many reporters name of 3 armour hospital oncology experts are not willing to evaluation"India edition"The therapeutic efficacy of drugs,They think,Unable to grasp these drug clinical trial data,Don't say curative effect,Even safety can't guarantee.In recent years,They have been met because the use of irregular drugs causing side effects and the patient.

　　“我曾经收治过不少本来在接受正规治疗的病人，病情已经受控，但后来擅自改吃一些从非法途径购买的药物，结果出现了发烧、白细胞增高、全身肌肉酸痛等反应。”广州一家三甲医院的血液科专家告诉记者，像慢性髓性白血病患者，格列卫是目前医学界公认的有效药物，但服药期间需要长期监测，“一些病人因为改吃‘印度药’，连医院都不来了，这样做其实非常危险。”

"I have had many were originally in the formal therapy of the patients,Condition has been controlled,But then do STH without authorization to eat some from illegal means to buy drugs,The results appeared to have a fever/Leucocyte heighten/Muscles ache reaction."Guangzhou a 3 armour hospital hematology department experts told reporters,As chronic myelogenous leukemia patients,Gleevec is the medical profession is recognized as one of the effective drug,But during the medicine need long-term monitoring,"Some patients because change to eat‘India medicine’,Even the hospital are not coming,Do this in fact is very dangerous."

　　而格列卫的正规生产厂家诺华制药的一名销售人员则告诉记者，通过非法途径购买的“印度版”药物由于完全没有监管，所以还存在买到假药的风险。“有些病人甚至吃了好几个月才发现买到的其实是不法分子用面粉制成的‘丸子’，耽误了宝贵的治疗时间。”

And gleevec of formal manufacturers novartis's a sales staff, told reporters,Through the illegal way of purchase"India edition"Drug because no supervision,So there are still buy counterfeit drugs risk."Some patients even eat for several month found that buy is actually illegal molecules made of flour‘balls’,Delay a valuable treatment time."

　　该销售人员还表示，按照印度医学界做的临床研究显示，这些药对于某些患者不仅没有疗效，甚至还可能诱发第二肿瘤。(记者周浩杰、黎蘅）

The sales staff also said,According to Indian medicine do clinical studies show that,These medicines for some patients not only no curative effect,May even cause a second cancer.(Reporter ZhouHaoJie/LiHeng)