肺结核是一种严重威胁人类健康的传染病。新中国成立60多年来，我国结核病疫情总体呈下降趋势。但由于多方面原因，结核病近年又卷土重来，呈现出感染人数多、新发患者多、复发患者多、耐药患者多、死亡人数多等新特点。

Tuberculosis is a serious threat to human health of infectious diseases.Since the founding of sixty years,Our country tuberculosis epidemic declined overall.Due to various reasons,Tuberculosis in recent years, stage a come back,Present a infection number/New cases of patients/Recurrence patients/Resistant patients/The death toll of new features.

　我国是耐多药结核病流行严重国家之一 Our country is resistant to many medicine tuberculosis popularity of the serious

　　目前全球有近1/3，即20亿人口感染结核菌，活动性肺结核病人约2000万，每年新发结核病人约800万-1000万，每年约有300万人死于结核病，75%的结核病死亡发生在最具生产力的年龄组。其中95%来自发展中国家。

Nearly a third of the world,That is 2 billion people infected with bacteria that cause tuberculosis,Active tuberculosis patients about 20 million,Each year about 8 million new cases of tuberculosis person - 10 million,Each year about 3 million people die from it,75% of TB deaths in the most productive age group.95% of them from developing countries.

　　早在1993年，世界卫生组织就宣布结核病已经进入全球紧急状态。我国是全球22个结核病流行严重的国家之一，同时也是全球27个耐多药结核病流行严重的国家之一。特别是耐药结核菌的出现以及结核病合并艾滋病毒感染，更为结核病的防治带来许多新问题。许多结核病控制专家甚至忧虑，如今由于耐药性结核病的出现，正在悄悄把我们带回无药可医的恐怖年代。

As early as in 1993,The world health organization declared TB has entered into the global state of emergency.Our country is global 22 tuberculosis popular one of the countries seriously,At the same time also is the global 27 resistance to many medicine tuberculosis popular one of the countries seriously.Especially the emergence of resistant n/med tuberculosis bacterium and tuberculosis combined HIV infection,More tuberculosis prevention brings many new problems.Many of the tuberculosis control experts even worry,Now due to the emergence of resistant tuberculosis,Are silently bring us back to no medicine can medical terrorist s.

系列理论误区导致人类走不出防治怪圈 A series of theoretical misunderstandings cause humans to go out control circle

　　导致人类走不出防治结核病怪圈的主要原因，是人类在结核病防治领域中存在的一系列理论误区。误区一：结核病是结核分枝杆菌引起的传染病，是全世界由单一致病菌导致死亡最多的疾病，而临床实践证明结核病是多种微生物交叉混合感染的结果。误区二：以全身应用抗结核药物为主的化学治疗是人类控制结核病的主要手段。在结核菌多耐药、耐多药和广泛耐药日益严重的今天，我们更要转变思维，重新思考。误区三：只要坚持长期、足量、联合、全程服用抗结核药物，就能治愈肺结核。事实证明，这种传统的化疗方法有难以坚持，毒副作用明显，对病人肝肾损害严重，导致其免疫力下降等诸多弊端。

Cause humans to go out the main reason for the prevention and control of tuberculosis circle,Is the human in the prevention and control of tuberculosis in the field of a series of theoretical misunderstandings exist.Error a:Tuberculosis is caused by mycobacterium tuberculosis infection,Is the world by a single pathogenic bacteria killed most of the disease,The clinical practice has proved tuberculosis is a variety of microbial cross mixed infection results.Error two:With systemic application of anti-tuberculosis drugs primarily chemical treatment is the main method to control human tuberculosis.In more than n/med tuberculosis bacterium resistance/Resistance to drugs and drug resistance more widely increasingly serious today,We also want to change thinking,rethink.Error three:As long as we persist in long-term/enough/joint/Taking the fight n/med tuberculosis medicaments,Can cure tuberculosis.Facts have proved,The traditional chemotherapy method is difficult to adhere to,Side effects obvious,The patient with severe damage,Lead to the immune system and so on many disadvantages.

单纯应用抗结核药物会破坏固有菌群平衡 Simple application anti-tuberculosis drugs can destroy natural flora balance

　　结核病患者的病灶中不仅有结核杆菌的存在，同时伴有多种致病微生物的寄生。因此，结核病灶是多种致病微生物混合感染的结果，单纯应用抗结核药物，常常不能有效地控制结核病。相反，会人为地破坏结核病灶内固有的菌群平衡，助长结核杆菌的抗药性和耐药性。

The focus of the TB patients not only have the presence of mycobacterium tuberculosis,At the same time with a variety of pathogenic microorganism parasitic.so,Tuberculosis stove is a variety of pathogenic microorganism mixed infection results,Simple application anti-tuberculosis drugs,Often can not effectively control tuberculosis.instead,Will human destruction in tuberculosis kitchen inherent flora balance,Encourage mycobacterium tuberculosis resistance and resistance.

　　其次，常规化疗全身给药的方法，不能保证结核病灶内的有效浓度，当常规化疗的临床效果不佳时，不能简单的归结为细菌的耐药性，其实，恰恰是我们药物浓度的不足才导致了细菌的耐药，这一点尤其应当引起我们的重视。

secondly,Conventional chemotherapy systemic delivery method,Can't guarantee the effective concentration in tuberculosis kitchen,When conventional chemotherapy the clinical effect of the poor,Not simple due to bacterial resistance,In fact,Just is our lack of drug concentration has led to the bacterial drug resistance,This is especially should cause our attention.

　　另外，结核病常规药物治疗过程中，只考虑了破坏、杀灭，没有考虑修复、重建，更没有考虑动态平衡。单纯靠全身用药能够彻底杀灭结核杆菌吗？当我们全身大剂量、长期化疗的时候，杀灭的不仅仅是结核杆菌，同时破坏的是菌群平衡，破坏的是机体自然免疫功能和保护屏障，不仅效果不佳，而且得不偿失。

In addition,Tuberculosis routine drug treatment process,Only considered the destruction/kill,Did not consider repair/reconstruction,The more did not consider dynamic balance.Simply by systemic drug can be completely kill mycobacterium tuberculosis?When we systemic large dose/The long-term chemotherapy,Kill is not only the mycobacterium tuberculosis,At the same time destroy is flora balance,The damage is the body's natural immune function and protection barrier,Not only the effect not beautiful,And the loss outweights the gain.

微创靶向综合疗法提供治疗新思路 Minimally invasive targeted comprehensive therapy treatment is provided new ideas

　　近年来，在国内兴起了微创靶向综合疗法研究。这是一种利用CT扫描技术对肺结核病灶进行全面立体直观的定位分析，并根据以往临床用药情况、细菌培养和药物敏感试验结果，有针对性地选择杀菌和促进结核病灶修复重建的独特配方，经皮肺穿刺空洞或病灶，直接注入临时配置的抗结核药液，再结合营养、运动和身心兼治的系统治疗方法。

In recent years,In China the rise of the minimally invasive targeted comprehensive therapy research.This is a use of CT scanning technology on tuberculosis lesions to conduct a comprehensive three-dimensional visual positioning analysis,And according to the previous clinical application situation/Bacterial culture and drug sensitive test results,Targeted to choose sterilization and promote restoration tuberculosis kitchen unique formula,Percutaneous lung puncture hole or lesions,Direct injection temporary configuration of anti-tuberculosis liquid medicine,Combined with nutrition/Sports and physical and mental and governance system treatment.

　　该疗法不仅可以直接经皮肺穿刺或空洞置管注药，以治疗巨大空洞，也可以经胸膜腔置管注药治疗脓胸和支气管胸膜瘘，同时可以经气囊导管向支气管内注药治疗支气管内膜结核，方法简单、操作灵活、标本兼治，而且治疗时间短、疗效显著、费用低廉、复发率低、副作用小。

The treatment can not only direct percutaneous lung puncture or empty catheter note medicine,To treat large hole,Can the pleural cavity catheter injection drug therapy and empyema BPF,At the same time can the balloon catheter to endobronchial note medicine treating bronchial endometrial tuberculosis,Method is simple/Operation agile/paper,And treatment time is short/Curative effect is distinct/Low cost/The recurrence rate is low/Little side effects.

　　此外，疗法具有广泛的适宜人群，如耐多药及广泛耐药性患者，急需快速治愈初治肺结核患者，不能耐受长期服药的肺结核患者，严重肝肾功能损害的肺结核患者，适宜有严重并发症的肺结核患者如大咯血患者，肺结核合并曲球菌、尘肺的患者，结核性脓胸、肺脓肿、支气管胸膜瘘的患者，结核性脑膜炎、淋巴结核、骨结核患者等。

In addition,Therapy has a wide range of appropriate crowd,Such as resistant to drugs and more widely in patients with drug resistance,Need fast cure tuberculosis patients,Can't withstand long-term medication of TB patients,Serious damage to kidney function of patients with pulmonary tuberculosis,Suitable for serious complications of TB patients such as big hemoptysis patients,Mycobacterium tuberculosis (MTB song cocci/Pneumoconiosis patients,Tuberculous empyema/Pulmonary abscess/BPF patients,Tuberculous meningitis/scrofula/Bone tuberculosis patients, etc.