中新网8月31日电 据国家食药监局网站消息，近日，媒体报道有企业使用掺有“地沟油”成分的豆油，生产7-氨基头孢烷酸(简称7-ACA)并销售给制药企业。国家食品药品监管局对此高度关注，已派出调查组展开调查，同时要求制药企业必须按规定对所购原料严格把关，对供货企业进行审计，严防不合格化工原料进入制药环节。

Beijing on August 31, according to the national food, the administration's web site message，recently，Media reports have mixed with enterprise use“Trench oil”Components of soybean oil，7 - production of 7-aminocephalosporanic acid(Referred to as 7 ACA -)And sales to pharmaceutical enterprise。State food and drug supervision bureau to high attention，Already sent investigation team investigating，At the same time the requirement pharmaceutical enterprise must follow a prescribed to buy raw materials strictly，The supplier audit enterprise，Take strict precautions against unqualified chemical raw materials into the pharmaceutical link。

　　7-ACA是用于生产头孢类抗生素的中间体，属于化工原料。化工企业生产7-ACA有两个步骤：首先是通过头孢菌发酵得到头孢菌素C，豆油是发酵过程的培养基成分之一，掺有“地沟油”成分的豆油就用在这个步骤；第二步是经过酶法或化学裂解法分离并提纯得到7-ACA。

7 - ACA is used in the production of cephalosporin antibiotic intermediates，Belongs to the chemical raw materials。Chemical enterprise production 7 - ACA has two steps：The first is through the cephalosporin bacteria fermentation by cephalosporin C，Soybean oil is fermentation process are one of the ingredients of medium，Mixed with“Trench oil”Components of soybean oil is used in this process；The second step is to after enzymatic or chemical cracking method separation and purification get 7 - ACA。

　　制药企业用7-ACA生产头孢类抗生素，还需要经过繁杂、精细的制造工艺，包括：衍生化、保护、接侧链、脱保护和成盐，以及分离提纯、重结晶等步骤，成为头孢类抗生素原料药，再通过制剂工艺，才能生产出口服、注射用的头孢类抗生素药品。

Pharmaceutical enterprise with 7 - ACA production cephalosporin antibiotic，Still need to pass multifarious、Fine manufacturing process，including：derivatization、protection、Joint side chain、Take off protection and into salt，Purification and separation、Recrystallization and steps，Become cephalosporins antibiotics API，Then through the preparation process，To the production of export clothing、Injection of cephalosporins antibiotics drugs。

　　国家食品药品监管局正在组织专家检索国内外有关文献，评估豆油质量对头孢类抗生素药品质量安全的影响，同时了解国外使用再生油的做法。专家认为，“地沟油制药”的提法不妥，易使公众误解；抗生素药品生产链条长、环节多，任何环节掺杂使假行为都应当受到谴责，并承担责任。

State food and drug supervision bureau is organizing experts retrieval relevant literature both at home and abroad，Evaluate the quality of soybean oil to cephalosporin antibiotic drug quality safety influence，At the same time to understand foreign using reclaimed oil practices。Experts say，“Trench oil pharmaceutical”Formulation not，Easy to make public misunderstanding；Antibiotic pharmaceutical production chain length、links，Any link doping ShiJia behavior should be condemned，And bear the responsibility。

　　国家食品药品监管局要求药品生产企业采取有力措施，严防不合格原料流入生产环节，同时加强油脂类原辅材料的检查，确保药品质量安全有效。

State food and drug supervision bureau for the pharmaceutical production enterprise take strong measures，Take strict precautions against the unqualified raw materials into the production links，At the same time, strengthen the grease kind of raw material inspection，To ensure the quality of drugs is safe and effective。