九成关节炎患者有胃肠道风险 Ninety percent arthritis patients risk of gastrointestinal tract

专家建议，在不伤及肠胃的前提下治疗关节疼痛应记住三个数字 Experts suggest,In the premise of intestines and stomach injury and treatment of joint pain should remember three digital

　　家住越秀区的陈老先生，身子骨一向硬朗。去年冬天查出关节炎后一直定期服用药物，关节疼痛控制得不错，每天打太极、喝早茶、带孙子，生活过得有滋有味。可是上周末，陈老先生却因为剧烈的腹痛和便血被送进了医院。诊断发现，陈老先生“胃壁可见多处溃疡面及出血点”，医生说如果没及时送到医院，可能会有生命危险。家人心有余悸之余，怎么也想不明白，陈老先生没什么肠胃上的毛病，好端端的怎会胃出血呢？医生表示，罪魁祸首正是陈老先生因为治关节炎而长期服用的止痛片。

Yuexiu district of living of Mr. Age,Once has always been hale and hearty.Last winter found out after arthritis has been regularly take drugs,Joint pain control well,Every day practicing tai chi/Drink tea/Belt grandson,Life. "so go to sleep.But last weekend,Mr. Age but because of severe abdominal pain and hemafecia was sent to the hospital.Diagnosis found,Mr Age"The hole in the stomach wall visible in ulcer surface and petechiae",The doctor said that if not promptly to the hospital,May have dangerous life.The family was over,How to also don't understand,Mr. Age not on intestines and stomach trouble,Good? How can stomach bleeding?Doctors say,Culprit is Mr. Age because cure arthritis and long-term use of painkillers.

止痛药埋下胃出血隐患 Painkillers buried stomach bleeding hidden trouble

　　“治疗关节炎多用非甾体类抗炎镇痛药(NSAIDs药物)，其中的非选择性NSAIDs药物对胃肠道损害严重，用药不当会引发胃肠道不良事件。”在近日召开的由中国医师协会风湿免疫专科医师分会主办的“中国关节炎患者胃肠道高危因素调研”终期数据发布会上，中国医师协会风湿免疫专科医师分会会长、北京协和医院风湿科主任张奉春教授介绍，在消化性溃疡患者中，29%的住院和25%~36.2%的死亡与应用非甾体抗炎药相关。可以说，非选择性NSAIDs药物是关节炎乃至所有疼痛人群胃肠道安全最可怕的隐患之一。

"Treatment of arthritis multi-purpose nonsteroidal anti-inflammatory analgesic(NSAIDs drug),One of the nonselective NSAIDs drugs on gastrointestinal tract seriously damaged,Improper use can cause gastrointestinal adverse events."In the recently held by the Chinese medical doctor association rheumatoid immune specialist branch of the host"China arthritis gastrointestinal risk factors research"Eventually period data conference,The Chinese medical doctor association rheumatoid immune specialist club President/Beijing union medical college hospital, director of the FengShiKe ZhangFengChun introduced professor,In peptic ulcer patients,29% of the hospital and 25% ~ 36.2% of the deaths, and application non-steroidal anti-inflammatory drug related.Can say,Nonselective NSAIDs drug is arthritis pain and all the crowd gastrointestinal safety hidden trouble of the worst.

　　在中国，像陈老先生这样的关节炎患者达一亿多人。最新发布的中国关节炎患者胃肠道高危因素调研结果显示，接近九成的关节炎患者具有一定程度的胃肠道风险，对于这些胃肠道本身就非常脆弱的患者来说，非选择性NSAIDs药物不啻于雪上加霜，引发消化道溃疡、出血、穿孔或梗阻等严重事件的概率就更大了。

In China,Like age like Mr Arthritis patients up to more than one hundred million people.The latest release of Chinese arthritis gastrointestinal risk factors research results show that,Nearly ninety percent of arthritis has a certain degree of risk of gastrointestinal tract,For these gastrointestinal itself is very fragile for patients,Nonselective NSAIDs drugs to the ornithological equivalent,Cause digestive tract ulcer/bleeding/A hole or obstruction and the probability of serious incident is bigger.

预防胃肠道出血记住三个数字 Prevent gastrointestinal bleeding remember the three figures

　　关节炎患者怎么判断自己的胃肠道状况是否处于高风险呢？如何才能在不伤及肠胃的前提下治疗关节疼痛呢？专家建议记住三个数字：

Arthritis how to judge their own gastrointestinal condition is in a high risk?How can the premise of intestines and stomach injury and treatment of joint pain?Experts suggest remember the three figures:

数字1：九类人群需关注胃肠道安全 Number 1:Nine group security need to be paid attention to the gastrointestinal tract

　　按照国际上通用的分类方法，引起严重胃肠道不良反应的危险因素主要包括以下九种：高龄(年龄≥60岁)、消化道溃疡史、使用抗凝剂、使用非选择性NSAIDs、使用糖皮质激素、使用低剂量阿司匹林、幽门螺旋杆菌感染、吸烟及酗酒。

According to common international classification method,Cause serious gastrointestinal adverse reaction risk factors mainly include the following nine:old(Age 60 years old or)/Digestive tract ulcer history/anticoagulation/Use nonselective NSAIDs/Use of glucocorticoid/Using low dose aspirin/Helicobacter pylori infection/Smoking and drinking.

数字2：止痛药有两种机制 Digital 2:Painkillers have two kinds of mechanism

　　大部分关节炎患者的胃肠道脆弱状态，和容易刺激肠胃的非选择性NSAIDs药物似乎成了一对不可调和的矛盾。对此，张奉春教授指出，抗炎镇痛是关节炎治疗的必要之举。目前市场上有两种不同机理的止痛药：非选择性NSAIDs药物虽然抗炎镇痛的作用达到了，但却引发各种胃肠道问题；随着医学的发展，科学家们研制出选择性NSAIDs药物，它可将胃肠道事件风险降低四倍。

Most arthritis gastrointestinal fragile state,And easy to stimulate intestines and stomach of nonselective NSAIDs drug seems to become a pair of irreconcilable conflict.this,ZhangFengChun professor noted that,Anti-inflammatory analgesic is necessary for the treatment of arthritis.On the market at present there are two kinds of different mechanism of analgesic drugs:Nonselective NSAIDs drugs although anti-inflammatory analgesic role reached,But cause various gastrointestinal problems;With the development of medical science,Scientists have developed a selective NSAIDs drugs,It can reduce the risk of gastrointestinal events four times.

数字3：用药之前多问一句 Digital 3:Medication before ask

　　就医时，应当详细告知自己的病史、用药史，以便医生给出更准确的用药指导；当医生开出NSAIDs药物或在药店购买NSAIDs药物时，请向专业人士多问一句，“这种药会伤害胃肠道吗？”争取从诊断到用药的每一个环节入手，实现真正有效、安全的抗炎镇痛。(记者 黎蘅)

When go to a doctor,Should be detailed to history/Medication history,,So that the doctor is more accurate medication guide;When the doctor open NSAIDs drugs or in the drugstore is bought NSAIDs drugs,Please ask professional personage to ask a,"This medicine will damage the gastrointestinal tract?"From diagnosis to use for each link of the,True effective/Safe anti-inflammatory analgesic.(Reporter LiHeng)