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国际“千人基因组计划”公布逾千人基因数据--亲稳舆论引导监测室
2012-11-02

  

“千人基因计划”公布逾千人基因数据 "One thousand people genome project"More than one thousand people by genetic data

  大型国际科研合作项目“千人基因组计划”的研究人员在新一期英国期刊《自然》上发布了1092人的基因数据,这一成果将有助于更广泛地分析与疾病有关的基因变异

Large international scientific research cooperation projects"One thousand people genome project"Researchers in the new period the British medical journal[natural]Published the 1092 people's genetic data,The results will help more widely analysis and diseases gene mutation.

  由中美英等多国科研机构联合发起的“千人基因组计划”最终目标是获得世界各地不同人群中2500人的基因数据。本次逾千名基因提供者来自欧洲、美洲、亚洲、非洲的14个国家和地区。

The United States and Britain, by many scientific research institutions jointly sponsored"One thousand people genome project"The ultimate goal is to get all over the world in different groups of 2500 genetic data.The more than gene provider from Europe/America/Asia/Africa's 14 countries and regions.

  这是科学界首次实现千人规模以上的基因组对比分析,这一规模可以帮助发现一些罕见的基因变异,比如携带者占总人口比例不到1%的基因变异。这些罕见基因变异或许与疾病有关,例如可能增加心脏病或癌症的患病风险,对基因变异进行研究有助于开发预防、治疗相关疾病的方法。

This is the first scientific community to realize scale above one thousand people a comparative analysis of the genome,This scale can help find some rare gene mutation,Such as carriers proportion less than 1% of the genetic variation.These rare genetic mutation may and diseases,For example may increase the risk of heart disease or cancer,Study of genetic variation to prevent development/Treat the method of related diseases.

  这份研究报告的主要作者、英国牛津大学教授吉尔·麦克韦恩说,根据已获得的基因数据,每个看起来很健康的人其实都携有数百个罕见的基因变异,其中有些基因变异已证实与某些疾病风险有关。这些基因变异究竟在什么情况下才会实际增加患病风险,是今后深入研究的目标。

The report's main authors/Oxford University professor, Jill mike WeiEnShui,According to the acquired genetic data,Each looks very healthy people actually all with hundreds of rare gene mutation,Some genetic variation has been confirmed with some risk for the disease.Whether the gene variants under what circumstances will actually increase the risk,Is the goal of further research.

  由于这1092名基因提供者的分布地域较广,此次发布的数据也为今后的基因研究提供了一份可供参考的“基因地图”。如果要对一个人的基因组进行分析,就可以不再泛泛地找一些人的基因组用于对比,而是直接调阅他们长期生活区域的人群基因组数据,开展更有针对性的比较。

Because this 1092 gene provider distribution of a wide area,The release of data but also for future genetic research provides a reference"Gene map".If you want to a person of the genome analysis,Can no longer generalities find some person's genome for contrast,But direct read their long-term living areas crowd genome data,To carry out a more targeted comparison.

  上述成果见证了基因组研究的快速发展,过去鼎鼎大名的“人类基因组计划”耗费10多年才在2003年绘出一个人的完整基因组图谱,而“千人基因组计划”自2008年启动以来,短短4年间就已获得超过1000人的基因组数据。(记者 黄堃)

The above results witnessed the rapid development of genome research,The past big names"The human genome project"Take 10 years in 2003 to draw out a person's entire genome map,and"One thousand people genome project"Since the 2008 years since the launch,Only four years has won more than 1000 person's genome data.(Reporter 黄堃)


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