中新社深圳11月19日(记者 郑小红)记者19日从深圳华大基因研究院获悉，一项历时两年之久、规模高达11105例病例的大规模临床研究显示，运用大规模平行测序的无创产前基因检测技术，将有助于对胎儿染色体数目异常进行产前筛查和健康预防。

China news agency shenzhen November 19,(Reporter ZhengXiaoGong)Reporter 19 from shenzhen huaqiao university institute of genes that,A lasted two years/Scale up to 11105 cases of large Numbers of clinical studies show,Using large scale parallel sequencing, non-invasive prenatal gene detection technology,Will help to fetal chromosome number anomaly in prenatal screening and health prevention.

　　由深圳华大基因研究院、深圳华大临床检验中心、首都医科大学、中国人民解放放军总医院、及其他国内二十多家医院合作完成，这项基于大规模平行测序的无创产前基因检测技术在胎儿染色体非整倍体检测中的临床应用评价结果，已于今年11月9日在《临床诊断》(PrenatalDiagnosis)杂志发表。

The shenzhen huada gene research institute/Shenzhen huada clinical examination center/Capital medical university/Chinese people's liberation army general hospital put/And he more than 20 domestic hospital collaboration,Based on the large-scale parallel sequencing, non-invasive prenatal gene detection technology in fetal chromosomal aneuploid detection the clinical application of evaluation result,Already this November 9, in[Clinical diagnosis](PrenatalDiagnosis)Magazine published.

　　据介绍，临床结果显示，NIFTY在21三体及18三体综合征的检测中具有高特异性和高敏感性。此外，研究人员还提出可以整合基于MPS的NIFTY检测技术，在中国建立新的筛查诊断模型等设想。据悉，胎儿染色体数目异常是一种偶发性疾病，迄今尚无有效的治疗方法，只能通过产前筛查、诊断等手段进行一定程度的预防。但目前传统的产前诊断多采用羊膜穿刺等侵入性取样方法，可能会导致感染并存在一定几率的流产等风险。

According to introducing,Clinical results show that,NIFTY in the 21st three body and 18 three body syndrome in detection with high specificity and high sensitivity.In addition,The researchers also put forward based on the integration of MPS NIFTY detection technology,The establishment of a new screening diagnosis model assumption.It is reported,Fetal abnormal chromosome number is a kind of sporadic disease,So far there is no effective treatment method,Only through the prenatal screening/Diagnosis means a certain degree of prevention.But at present, the traditional prenatal diagnosis with amniotic membrane puncture and invasive sampling method,Could lead to infection and has a chance of abortion and risk.

　　不过该项技术的临床应用，还将面临很多问题，如这种新的方法可对性染色体进行检测，其中包含有胎儿的性别信息。但依据中国当前状况，禁止非医学用途在胎儿出生前公开性别信息。

But the technology of clinical application,Also will face a lot of problems,If this new method can be applied to detect sex chromosome,It contains information that the gender of the fetus.But according to China's current situation,Ban non-medical USES in fetal birth gender public information.

　　深圳华大基因研究院表示，大规模临床研究表明，这一产前检测技术有着更高的精度和安全性，该机构预计在不久的将来，这种检测技术可能会比传统检测更为便宜，有可能从根本上改变传统的产前检测及诊断。(完)

Shenzhen huada gene research institute said,Large-scale clinical research shows that,The prenatal detection technology have a higher accuracy and safety,The agency is expected in the near future,This kind of testing technology may be less than the traditional detection more cheap,May fundamentally change the traditional prenatal detection and diagnosis.(finish)