肺癌的预防之道就是远离香烟和烟雾，控制吸烟可以减少80%以上的肺癌 The way of the prevention of lung cancer is far from the cigarette and smoke,Tobacco control can reduce more than 80% of all lung cancer

　　肺癌已成为癌症中的“超级杀手”，我国肺癌死亡率与30年前相比上升了465%，同时，肺癌发病人群也高居榜首，肺癌发病率逐年升高已经成为非常严峻的社会问题。在日前举行的以“引领变革，成就未来”为主题的肺癌治疗峰会上，中国医学科学院肿瘤医院孙燕院士对于国内肺癌发病率逐年升高的现状表示担心，他表示，一些不良生活习惯是肺癌发病的主要原因，比如吸烟。肺癌的预防之道，就是远离香烟和烟雾，控制吸烟可以减少80%以上的肺癌，肺癌的发病率和死亡率都会随着戒烟时间的延长而逐渐降低，如果连续戒烟12年，则可与不吸烟者接近。另外，远离污染环境也是肺癌的有效预防之道。

Has become the cancer of the lung cancer"Super killer",Lung cancer mortality in China rose by 465% compared with 30 years ago,At the same time,Lung cancer also topped the crowd,Lung cancer incidence increased year by year has become a very serious social problem.To at present"Leading change,Achievements in the future"As the theme of the summit in lung cancer treatment,Academician of Chinese academy of medical sciences cancer hospital Sun Yan for domestic worry about the present situation of the incidence of lung cancer increased year by year,He said,Some bad living habits is the main cause of lung cancer,Such as smoking.The prevention of lung cancer,Is far away from the cigarette and smoke,Tobacco control can reduce more than 80% of all lung cancer,The morbidity and mortality of lung cancer will gradually decreased with longer duration of smoking,If you quit smoking for 12 consecutive years,Can move closer to non-smokers.In addition,Away from the pollution of the environment is also the effective way of prevention of lung cancer.

预防肺癌要远离香烟和烟雾 Prevent lung cancer to stay away from cigarette and smoke

　　据孙燕院士介绍，我国拥有3亿多烟民，男性吸烟者肺癌的死亡率是不吸烟者的8~20倍。空气污染的环境加上吸烟，会诱发癌症。北京宣武医院支修益教授表示：“肺癌的预防之道，就是远离香烟和烟雾。不但不要吸烟，而且也不要让自己吸上二手烟，即使是在公共场所也应该设法避开那些吞云吐雾者，以避免受到二手烟的危害。”有关资料显示，控制吸烟可以减少80%以上的肺癌，肺癌的发病率和死亡率都会随着戒烟时间的延长而逐渐降低，如果连续戒烟12年，则可与不吸烟者接近。另外，远离污染环境，防止有些危害物感染也是预防肺癌的重要措施。

According to Sun Yan academicians,Our country has more than 300 million smokers,Male smokers lung cancer mortality rate is 8 ~ 20 times of the non-smokers.Air pollution in the environment with smoking,Causes cancer.Beijing xuanwu hospital yi professor said:"The prevention of lung cancer,Is far away from the cigarette and smoke.Not only don't smoke,But also don't allow yourself to smoke secondhand smoke,Even if is also should try to avoid those smoking in public places,In order to avoid the dangers of secondhand smoke."Relevant data shows,Tobacco control can reduce more than 80% of all lung cancer,The morbidity and mortality of lung cancer will gradually decreased with longer duration of smoking,If you quit smoking for 12 consecutive years,Can move closer to non-smokers.In addition,Away from the pollution of the environment,To prevent the infection of some of the hazards is the important measure to prevent lung cancer.

基因突变检测 肺癌治疗的好帮手 Good helper for mutation detection in lung cancer treatment

　　在肺癌治疗领域中，个体化治疗已成为新趋势，主要是因为对肿瘤分子生物学的深入研究，发现肿瘤有一些特殊的基因改变，或者是特殊的生物学指标，这些指标如果被拿来作为一个靶子攻击，选择性就会高很多。比如肺癌的个体化治疗，表皮生长因子受体基因的突变会导致肺癌的发生，或使肺癌的生长更快，如果能够针对这样的靶点来做治疗，相对来讲，毒性就会小很多，这也就意味着，治疗从原来单一的化疗，转变为更加个体化、更有针对性的治疗模式。

In the field of lung cancer treatment,Individualized treatment has become a new trend,Mainly because of tumor molecular biology research,Tumor found some special genetic changes,Or is a special biological indicators,If these indicators are intended as an attack target,Alternative would be a lot higher.Such as the individualized treatment of lung cancer,Epidermal growth factor receptor gene mutations can lead to the occurrence of lung cancer,Or make the lung cancer grows faster,If able to do against such targets for treatment,relatively,Toxicity will be much smaller,This means,From the original single chemotherapy treatment,Shift to a more individualized/More targeted treatment mode.

　　广东省人民医院副院长吴一龙教授就基因突变检测在肺癌治疗中的重要作用做了详细说明：“我国肺癌的治疗从最早的病理分析型到现在的基因指导下的靶向治疗，可以说是一个跨时代的进步，这种进步为我国肺癌晚期患者带来了更多的生存机会，而基因检测正是指导临床使用靶向治疗的重要依据。”

Wu Yilong professor, vice President of the people's hospital of guangdong province is the important role of detection of gene mutation in lung cancer treatment has made the detailed description:"The treatment of lung cancer in our country from the earliest pathologic type analysis to the current gene under the guidance of targeted therapy,It is across the progress of The Times,This progress for our country to bring more chances of survival in patients with late lung cancer,And genetic testing is the important basis to guide the clinical use of targeted therapy."

　　从分子水平上看，基因突变是指基因在结构上发生碱基对组成或排列顺序的改变。分子靶向药物的出现，使EGFR基因突变的晚期非小细胞肺癌患者可在被诊断初期就选用比化疗更有效、耐受性更好的靶向药物治疗方案。医生可以通过ARMS等方法将EGFR突变阳性的患者甄别出来。随着EGFR基因等生物标志物研究的明确，目前晚期非小细胞肺癌已从原先千篇一律以化疗为主的模式转变为以生物标记物为指导、结合组织学类型的治疗模式，肺癌的治疗将根据其肿瘤驱动基因的异常状况，个体化地选择靶向药物治疗。

Look from the molecular level,Gene mutation is refers to the base pair in the structure or change the order.The emergence of molecular targeted drugs,Make the EGFR gene mutation of advanced non-small cell lung cancer patients will be selected in the early diagnosis is more effective than chemotherapy/Tolerance better targeted drug therapy.The doctor can through such means as very different to EGFR mutation positive patients were screened out.As the biological markers, such as EGFR gene research clear,Advanced non small cell lung cancer has been increased from monotony to chemotherapy is given priority to the paradigm shift is guided by the biomarkers/Combined with the histologic types of treatment mode,The treatment of lung cancer will be according to the tumor drive abnormalities in genes,Individual to choose targeted drug therapy.

　　吴教授同时表示：“基因检测并不是非常复杂，卫生部最新发布的《三级肿瘤医院评审细则》明确要求医院要具备EGFR突变检测等分子诊断能力，目前国内已经有50多家大型的三甲医院和肿瘤专科医院具备了检测EGFR突变的能力。卫生部临床病理质控中心已经组织国内50多家医院参与全球EGFR检测质控网络，并组织建立国内自己的质控体系，确保检测的准确性。”

Professor wu said at the same time:"Genetic testing is not very complicated,The ministry of health's latest[Level 3 tumor hospital evaluation rules]Definitely require hospitals to EGFR mutation detection of molecular diagnostic ability,Currently has more than 50 domestic big 3 armour hospital and tumor specialized subject hospital have the ability to detect EGFR mutations.Clinicopathological quality control center of the ministry of health has organized more than 50 domestic hospital to participate in the global network of EGFR testing quality control,And organize the domestic set up our own quality control system,Ensure the accuracy of detection."

　　虽然目前晚期肺癌还不能治愈，但很多患者的生存期不但可以延长，而且可以明显提高生活质量。“特别是靶向药物的问世，改变了我们对于晚期非小细胞肺癌的治疗模式。靶向药物同传统药物相比，针对性更高，疗效显著，可以有效延长患者的生存期，对于无进展生存期和缓解率有所改善，与此同时，还可以减少患者的不良反应，提高患者的生活质量。”支修益教授表示。急性荨麻疹原因难找

Although the late lung cancer cannot be cured,But a lot of life not only can be extended,And can significantly improve the quality of life."Especially targeted drugs,Changed our model in the treatment of advanced non-small cell lung cancer.Targeted drugs compared with traditional medicine,More targeted,Curative effect is distinct,Can effectively prolong patient survival,For progression-free survival and response rate improved,At the same time,Also can reduce the adverse reaction of patients,Improve the patient's quality of life."A good professor said.Acute urticaria reasons hard to find