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姐妹三人均患有罕见家族性疾病 高血压不孕不育--亲稳网络舆情监控室
2012-08-09

  

姐妹三人都患高血压还不孕 All three sisters have high blood pressure also infertility

  

一查竟是同时患上罕见家族性泌尿系肿瘤,可能是基因突变引起 A check is also suffer from a rare tumor familial urinary tract,May be caused by genetic mutations

  因为同时患上高血压,并且时常感到乏力,来自外地的姐妹花三人同时到江苏省中医院进行治疗,而最终的诊断结果让省中医院的专家们都有些惊讶,姐妹三人患上的是罕见的家族性泌尿系肿瘤“肾上腺髓性脂肪瘤”。该院泌尿外科主任、著名泌尿外科专家顾晓箭教授告诉记者,目前国内外临床上都没有报道过的罕见家族性泌尿系肿瘤,姐妹三人几乎同样症状的泌尿系肿瘤更是少之又少。

Because at the same time suffer from high blood pressure,And often feels weak,From the field of sisters flower three people in jiangsu province and to hospital for treatment,And the final diagnosis let province of hospital experts are surprised by,The three sisters of people with is the rare familial urinary tract tumors“Adrenal medullary lipoma of the sex”。The hospital uropoiesis surgical department director、Famous urology experts GuXiao arrow professor told reporters,Both at home and abroad are no clinical reported rare familial urinary tract tumors,The three sisters people almost the same symptoms urinary tract tumor is more little little。

  记者了解到,三姐妹在就诊前有着相似的症状:月经不规律,结婚后一直未能怀孕,经常浑身乏力,患有高血压。两个妹妹还有中风的症状。在当地医院的初步检查发现,这三人的肾脏附近长有较大的瘤,但难以确定是何种肿瘤。当地医生推荐她们到省中医院泌尿外科进一步诊治。接诊后,专家们随即对三姐妹进行细致全面的检查,诊断出三姐妹中的大姐、二姐双肾同时患有肾上腺髓性脂肪瘤,小妹病情相对较轻,左肾患有髓性脂肪瘤。根据三人各自的病情和身体状况,专家为其制定了合理的治疗方案。两个星期前,老二先接受了手术,顾晓箭带领手术团队顺利切除患者左侧肾脏旁直径20多公分的肿瘤,大姐也在上个星期接受了肿瘤切除手术,术后恢复良好;小妹的肿瘤切除手术也将在近期实施。

The reporter understands,Three sisters before the interview with similar symptoms:Menstruation is not law,After getting married, had been unable to get pregnant,Often tired,People with high blood pressure。Two sisters and stroke symptoms。In the preliminary tests found that the local hospital,The three men to kidney have large tumors near long,But difficult to determine what kind of tumor。Local doctors recommend them to provincial hospital urology further treatment。After accepts,Experts immediately to the three sisters are meticulous and overall inspection,Three sisters diagnosed the elder sister、Two elder sister bilateral renal also suffer from adrenal medullary lipoma of the sex,Kid sister relatively light condition,The left kidney with myeloid lipoma。According to the condition of each one of the three and body condition,Experts for its a reasonable treatment options。Two weeks ago,The first had the surgery,GuXiao arrow led the surgical team on the left side of the kidney patients with smooth resection of the tumor more than 20 centimeters in diameter,Big sister also in last week accepted tumor resection,Postoperative recovery good;Kid sister tumor resection operation will also in recent implementation。

  顾晓箭说,肾上腺髓性脂肪瘤是本身就较为罕见的肾上腺肿瘤中的一种,发病率在肾上腺肿瘤中只占到了百分之十不到,是临床上较为罕见的无内分泌功能的良性肿瘤,因大多数无临床症状,因而很容易漏诊。近年来随着健康体检的普及和影像技术水平的提高,临床检出率明显提高,偶发患者比例逐渐升高。一般情况下,男性较多,而且是单侧发病。临床病例显示,该肿瘤并没有遗传性,也从未在得此病的患者亲属中发现有相同或相似病例。三姐妹同患肾上腺髓性脂肪瘤,而且都有相同症状的,目前在国内外临床医学界尚属首次。

GuXiao arrow said,Adrenal medullary lipoma is sex itself is relatively rare adrenal tumors in a,The incidence of adrenal tumors only up to ten percent less than,Is clinically more rare benign tumor of no endocrine function,For most no clinical symptoms,So it's easy to misdiagnosis。In recent years, with the popularity of the physical examination and the rise of the technical level of the image,Clinical detection rate increased significantly,Patients with occasional proportion is increasing gradually。In general,Men more,And it is unilateral disease。Clinical case indicates that,The tumor and no hereditary,Never in patients with the disease was found to have relatives of the same or similar cases。Three sisters with adrenal medullary lipoma with sex,And have the same symptoms,Currently in clinical medicine at home and abroad which is first。

  对于姐妹三人同时得病的原因,专家分析可能是家族性基因突变引起。“产生肾上腺髓性脂肪瘤的具体原因医学上目前不是特别清楚,心理压力过大,长期处在高压中,或饮食不平衡都有可能诱发。”而另一种情况则由于染色体突变或者缺失,造成基因异常,还有一些疾病,如高血压、过度肥胖都与其有密切关系。(通讯员 孙茜 冯瑶 记者 杨甜子)

For the three sisters people at a source of illness,Expert analysis may be caused by familial gene mutations。“Produce adrenal medullary lipoma of the specific reason for the medicine at present is not particularly clear,Psychological pressure,For a long time at high pressure,Or diet balance is not may cause。”And another case, the chromosome mutation or missing,Cause abnormal gene,And some disease,Such as high blood pressure、Obesity is closely related to all relationships。(Correspondent SunQian FengYao reporter Yang sweet son)


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