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研究人员研制抗癌药未果 意外获得男性避孕药--亲稳网络舆情监控室
2012-08-18

  一直以来,口服避孕药似乎只是女性的“专利”。美国研究人员研制一种抗癌药物时发现它具有成为男用避孕药的“潜质”,且不会产生令人不快的副作用。

Has been,Oral contraceptive seems to be female“patent”。Researchers in the United States to develop a cancer drug found that it has become a male contraceptive pill“potential”,And won't produce unpleasant side effects。

  或许今后,男性也可以通过每日或每周服用避孕药,与伴侣一同分担家庭计划的责任。

Perhaps in the future,Men can also through the daily or weekly taking the pill,Together with a partner to share the responsibility of family planning。

  

效果好 Effect is good

  波士顿戴纳-法伯癌症研究所的詹姆斯·布拉德纳与休斯敦贝勒医学院的研究人员一起研制出这种名为“JQ1”的药物。

Boston Dana - faber cancer institute James brad nano and baylor college of medicine in Houston, researchers developed with this name“JQ1”drugs。

  研究人员在17日出版的美国《细胞》杂志中写道,“JQ1”不含激素,可以阻断精子形成的关键过程。老鼠实验显示,若服用剂量正确,老鼠仍能对异性保持“性趣”,进行正常性活动,但无法繁殖后代。一旦停药,它们的繁殖能力迅速恢复,后代的大小、健康状况以及繁殖能力都不受影响。

Researchers in the issue of the United States《cell》Wrote in the journal,“JQ1”Don't contain hormone,Can block the spermatogenesis of key process。Mouse experiments show that,If the right dose,The mouse can still keep to the opposite sex“Twice the”,To normality activities,But not one that can reproduce。Once the drug withdrawal,Their ability to reproduce rapid recovery,The size of the offspring、Health and ability to reproduce would not be affected。

  “JQ1”的另一优点是可以以片剂的形式存在。当前大部分男用避孕用具是针剂或者贴片。

“JQ1”Another advantage is that it can exist in tablet。The current most male contraceptive is injection or SMT。

  英国《每日邮报》16日援引布拉德纳的话报道:“我们的发现证明,给老鼠服用后,这种化合物能对精子数量和活动能力产生迅速、可逆的影响,从而达到避孕的效果。”

British《Daily mail》16 quoted brad's words reports:“Our findings prove,After taking to mice,The compound to sperm number and activity ability produce quickly、Reversible influence,So as to achieve the effect of the birth control。”

  

意义大 Great sense

  研究人员说:“高比例的计划外妊娠与缺乏男性避孕替代方式有关……这会令孕妇死亡率上升,也会导致流产,从而带来道德、社会与财务问题,还会令单身母亲的数量增加。”

The researchers say:“The high proportions of unplanned pregnancy and lack of male contraception alternative way about......This will make the maternal mortality rate rise,Also leads to abortion,Thus to bring moral、Social and financial problems,Also can make increase in the number of a single mother。”

  如果这种男用口服避孕药研发成功,将成为避孕套问世数百年后第一款有效、非永久性的男性避孕用具。

If the male oral contraceptive research and development success,Will be the advent of condom hundreds of years later in the first paragraph of effective、Deciduous male contraceptive。

  不过,布拉德纳的合作伙伴、曾参与壮阳药万艾可(俗称“伟哥”)研发的迈克·怀利说,“JQ1”不能完全阻止精子产生,“受精是卵子和一个精子的交互作用。数据显示,没有成功率百分之百的避孕方法”。

but,Brad's partner、Participated in aphrodisiac viagra(Commonly known as“viagra”)Research and development of mike wyllie said,“JQ1”Can't completely prevent sperm production,“Fertilization is an egg and a sperm interaction。Data display,No success rate one hundred percent of contraceptive method”。

  待检验 For inspection

  布拉德纳说,他与合作伙伴研制癌症药品时无意发现药物的避孕作用。如今,他们正在进一步改良这种药物。不过,鉴于新药需要经过大量临床实验才能上市,因此,男用口服避孕药可能还需要很长时间才能和普通消费者见面。

Brad nano said,He and cooperation partners develop cancer drugs has no intention of drugs found contraceptive effect。now,They are further improved the drug。but,In view of the new drug need to pass a large number of clinical trials can be listed,therefore,Eisenhower oral contraceptives may need a long time to meet and average consumer。

  设菲尔德大学生殖专家艾伦·佩西说,研制出无激素男性口服避孕药的“大门已经打开……虽然不能预计临床实验的成败,但这的确值得一试”。

Set feld university fertility experts Alan Percy said,Developed no hormone men of oral contraceptives“The gate open...Although can not predict the success or failure of the clinical trials,But it is really worth a try”。

  男用口服避孕药能否为人广泛接受还是一个问题。

Eisenhower oral contraceptive whether humanness is widely accepted is still a problem。

  怀利说,“市场研究显示,不少女性宁愿自己肩负起避孕的责任,不愿依靠伴侣”,这是因为她们不能确定对方是否服用避孕药物。另外,男性是否愿意接受会抑制他们生殖能力,哪怕只是暂时抑制的药物?(新华社电 荆晶)

Wyllie said,“Market research shows that,Many women prefer their shoulder the responsibility of contraception,Don't want to rely on partner”,This is because they are not sure if the other party taking contraceptive drugs。In addition,Men willing to accept will suppress their reproductive ability,Even if it's just a temporary suppression drugs?(Xinhua JingJing)


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