科学现场 Science field

类艾滋病来了，比艾滋病差远了！ AIDS to the class,Far worse than the HIV/AIDS!

　　初看上去，阮金(Kim Nguyen)再普通不过。

At first glance,RuanJin(Kim Nguyen)More common, but.

　　这位生活在美国田纳西州的女人，喜欢穿一件浅黄色衬衫，并搭配暗紫色半框眼镜和亮闪闪的耳钉。只不过，这位越南裔裁缝极为瘦弱，一枚金戒指戴在她那像枯树枝一样的左手无名指上，晃得几乎能发出声音来。

The life in the us state of Tennessee woman,Like to wear a pale yellow shirt,And collocation dark purple half frame glasses and bright sparkling stud earrings.just,The Vietnamese origin tailor is extremely thin,A gold ring on her like KuShuZhi same ring finger,Sway almost can sound to.

　　但最近，一篇刊登在国际医学权威期刊《新英格兰医学杂志》上的文章，让这个普通的中年妇女为世人所知。

But in recent,An article published in the international journal of medical authorities[The New England journal of medicine]Articles on,Let this ordinary middle-aged woman known to the world.

　　从2009年开始，阮金持续发烧，全身骨骼感染，并伴有其他奇怪的病症。当她向美国国家过敏症和传染病研究所科学家莎拉·布朗(Sarah K. Browne)求助时，已经是重病缠身。布朗博士发现，这位病人的免疫系统已经无法正常运转，难以像健康人那样抵御病菌的侵害，“好像得了艾滋病，但是艾滋病病毒抗体检测呈阴性”。

Begin from 2009,RuanJin persistent fever,Whole body bone infection,Accompanied by other strange disease.When she went to the national institute of allergy and infectious diseases scientists Sarah brown(Sarah k. Browne)For help,Is very ill.Dr. Brown found,The patient's immune system has been unable to normal operation,Hard to like that healthy people to resist the enroach on of germs,"Like AIDS,But the AIDS virus antibody test is negative".

　　在这篇发表于2012年8月23日的论文中，布朗及其团队将阮金所患的怪病命名为“成人始发的免疫缺陷症”。这位女科学家解释说，这是另外一种获得性免疫缺陷症，多发于50岁左右的成年人。

In the article, published on August 23, 2012 in the paper,Brown and his team will RuanJin had strange disease named"Adult originating immune disease".The female scientists explained,This is another kind of acquired immune deficiency syndrome,Happens in about 50 of adults.

　　由于搜集的病例均为亚洲人，参与研究的中国台湾学者又将其称为“亚洲新型免疫缺陷症”。这种疾病与艾滋病晚期的临床症状极为相似，率先进行报道的美联社，给它取了一个醒目的名字——“类艾滋病”。国内很多媒体在转载时，又将这种疾病“专门针对黄种人”拎出来作为标题，引起了不小的恐慌。

Because collecting cases are asians,Participate in the study of Chinese Taiwan scholars and its called"Asian new immune disease".This kind of disease and AIDS late clinical symptoms are very similar,Take the lead in the ap reported,Give it took a striking name --"Kind of AIDS".A lot of domestic media in the transfer,And this kind of disease"Specifically for the yellow race"Carry out as a title,Caused a lot of panic.

　　为此，布朗对中国青年报记者特意作出澄清：“它与艾滋病有着显著的区别，既非由病毒引起，也不会传染。”

therefore,Brown told the China youth daily reporter specially clarification:"It has obvious difference with AIDS,Is neither caused by viruses,Also won't infect."

类艾滋病一直存在，只是知识还没有进步，当时还没有办法了解 Class AIDS there has been,But knowledge is not progress,When there is no way to know

　　早在向布朗求助之前，阮金就饱受类艾滋病的折磨。“我感到头晕和头痛，快要垮掉了。”阮金对美联社记者说，“我几乎吃不下任何东西。”

As early as in before to brown for help,RuanJin has been kind of living with HIV."I feel dizzy and I have a headache,Breaking down."RuanJin told the Associated Press,"I almost can't eat anything."

　　几年下来，她的体重从41公斤降到了31公斤。来自田纳西州杰克逊诊所的小卡尔顿·海斯第一次为她诊疗时，被眼前这位瘦骨嶙峋的女人吓坏了。海斯说：“她因为全身性的感染而变得羸弱不堪，乍看上去就像得了肺结核。”

A few years down,Her weight from 41 kg dropped to 31 kg.Tennessee Jackson clinic little Carlton hayes for her when the first diagnosis and treatment,Be eyes the bony woman scared.Hayes said:"She because systemic infection and become thin and weak unbearable,At first glance like had tuberculosis."

　　布朗发现，这个62岁的女人体内产生了一种名叫“具中和力的抗γ干扰素自体抗体”的物质。这种物质能够阻断伽马干扰素在免疫系统中发出清除感染的讯息。一旦阻断了这一讯号，患有获得性免疫缺陷症的病人，就很容易受到病毒、真菌和寄生虫，尤其是分枝杆菌的侵害。

Brown found,The 62 - year - old woman, the body produces a name"A neutral force resistance gamma-interferon autoantibodies"material.This substance is blocking gamma interferon in the immune system in a clean the infected messages.Once the blocking the signal,With acquired immune deficiency syndrome patients,Is very vulnerable to viruses/Fungi and parasites,Especially the enroach on of mycobacteria.

　　参与研究的台湾成功大学临床医学研究所所长谢奇璋教授解释说，这会导致“免疫力暴冲”现象的发生，即免疫控制失效而产生的自体免疫反应。患者会产生特别的抗体攻击免疫系统，导致免疫力下降，从而难以抵挡分枝杆菌、沙门氏菌以及一些霉菌的感染。

Participate in the study of Taiwan university of successful clinical medical institute director XieJiZhang professor explained,This will lead to"Immunity sudden attack"Phenomenon happened,The immune control failure resulting from the autoimmune reaction.Patients can produce special antibody against the immune system,Which can impact on their immune system,Thus difficult to resist mycobacteria/Salmonella and some mycotic infection.

　　“特别是分枝杆菌，在这种免疫缺损症的病人身上，会造成严重的散布性感染，有时候甚至会危及生命。”谢奇璋强调道。

"Especially mycobacteria,In this kind of immune QueSunZheng patients,Will cause serious spread infection,Sometimes even life-threatening."XieJiZhang insisted.

　　这也是人们将阮金所患的疑难杂症与艾滋病联系起来的原因。“它之所以被称为‘类艾滋’，是因为它也是一种免疫缺陷综合征，易造成患者的某些感染，并且其中一些感染与艾滋病患者如出一辙。”布朗表示。

This also is people will RuanJin have incurable diseases and AIDS the cause of the link."It is called‘Kind of AIDS’,Because it is also a kind of immune deficiency syndrome,Easy to cause some of the infection patients,And some of the infection and AIDS patients be exactly the same."Brown said.

　　不过，这种被媒体炒得沸沸扬扬的疾病，在北京协和医院艾滋病诊疗中心主任李太生看来，“并不是一种新的疾病，至少在临床上不是，此前在我们医院也发现过这种病例，但是很少，并且都已治愈”。

but,The media speculation an uproar in the disease,In the Beijing union medical college hospital, director of the center for AIDS diagnosis and treatment LiTaiSheng looks,"And is not a new diseases,At least not in clinic,Previously in our hospitals also found this case,But few,And were all cured".

　　谢奇璋也记得，30多年前，当他还在台湾大学医学系读书时，就有教授称看到过这样的病人，还纳闷说：“奇怪了，这是怎么回事？”

XieJiZhang also remember,More than 30 years ago,When he was in Taiwan university school of medicine, while reading,There is the professor says seen such patients,Also wonder said:"strange,This is how to return a responsibility?"

　　这位免疫学博士已经记不清楚，究竟是在大学几年级听哪个老师提到此病。但他表示，当时的患者也具备成人始发的免疫缺陷症的临床表现：一是反复性的感染分枝杆菌或者是沙门氏菌；二是只在成年人身上才发生。

The immunology doctor has can't remember,What is a few grade in college to listen to what the teacher mentioned the disease.But he said,The patient also have adult originating immunodeficiency disease clinical performance:One is repetitive infection mycobacteria or salmonella;The second is only in adults just happen.

　　“我认为一定是一样的病人，这个疾病是一直在的，只是知识还没有进步，当时还没有办法了解。”他对中国青年报记者说。

"I think that must be the same patient,The disease is always in,But knowledge is not progress,When there is no way to know."He told China youth daily reporter said.

　　不过，来自北京大学第一医院感染疾病科主任医师徐小元教授指出，所谓的类艾滋病在临床鉴别诊断中，更像是特发性CD4+T淋巴细胞减少症，“类艾滋病”只是它的“小名”。

but,From Peking University first hospital infection diseases department chief physician XuXiaoYuan professor noted that,The so-called kind of AIDS in clinical differential diagnosis,More like idiopathic CD4 + T lymphocyte reduce disease,"Kind of AIDS"Just it"Childhood name".

　　他解释说，这种十分罕见的综合征又被称为HIV阴性AIDS样综合征，早在1989年被德国的海纳·道斯教授等人首先报告，发表于国际医学权威期刊《柳叶刀》。这种疾病的临床表现类似艾滋病，同样也没有HIV感染证据。

He explained that,This is very rare syndrome is also known as HIV negative AIDS sample syndrome,As early as in 1989 by German wave professor dodds, first report,The international medical journal published authority[The lancet].This kind of the clinical manifestations of diseases like HIV/AIDS,Also no HIV infection evidence.