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加拿大学者找到心律不齐“原凶”--亲稳网络舆情监测室
2013-02-21

  中新社多伦多2月19日电 “心律不齐”是常见疾病,严重时可能致命。不列颠哥伦比亚大学学者利用强大X光重组一些过去显微镜无法观察到的病理活动,找到了造成心跳不规律的“原凶”。

China news agency on February 19, Toronto "arrhythmia"Is a common disease,Serious when can be deadly.The university of British Columbia scholars use powerful X-ray restructuring some past microscope can't observed the pathological activities,To find the cause of the irregular heartbeat"Former fierce".

  长期以来“心律不齐”困扰着全世界不少患者,这种心跳过快或过慢的不规则症状,可能导致心悸、晕眩、昏迷,严重时甚至会致命,但其成因一直是个谜。

For a long time"arrhythmia"Plagued by many patients around the world,The heart beat too fast or too slow irregular symptoms,May cause heart palpitations/dizzy/coma,Serious or even fatal,But its origin has always been a mystery.

  不列颠哥伦比亚大学分子生物学家彼得杰所带领的团队,利用强大X光重组一些过去显微镜无法观察到的病理“犯罪现场”,并逮到“现行犯”。

The university of British Columbia molecular biologists Peter jie with team,Use powerful X-ray restructuring some past microscope can't observed pathology"The scene of the crime",And caught"Flagrante delicto".

  彼得杰指出,人类心脏跳动必须仰赖钙质,每次心跳前,钙离子会涌入心肌细胞中,接着一种特殊蛋白质会在细胞中形成一条通道,让这些钙离子从细胞中释出,导致心脏收缩。

Peter jie pointed out that,The human heart beating must rely on calcium,Before each heart,Calcium ion will into myocardial cells,Then a kind of special protein in cells form a channel,Let the calcium ion release from the cells,Cause cardiac contraction.

  一旦形成这种特殊蛋白质的基因发生突变,就会造成心律不整,让原本健康的人突然因心脏病发而死亡。

Once formed the special protein gene mutations,Can cause cardiac arrhythmia,Let originally healthy people suddenly because of heart attack and death.

  他说,重建钙离子通道及运行动态,让研究人员观察到整个心律不齐的发生过程,原来是基因突变让通道结构变得不稳定,让钙离子提前从细胞中释出,导致心律不齐。未来只要找出稳定的“钙离子通道”,即可预防心律不齐,挽救无数病患生命。

He said,Reconstruction of calcium ion channels and operation dynamic,Let the researchers observed the whole process of the occurrence of arrhythmia,The original is the gene mutation let channel structure become unstable,Let the calcium ion advance from cells release,Cause arrhythmia.The future as long as find stable"Calcium ion channels",Can prevent arrhythmia,Save countless patients life.

  据此间的世界日报报道,这项重大突破18日在波士顿举行的美国尖端科学协会(AAAS)年会上发表,并以3D动画模式让与会学者目睹整个心律不整的病理成因。

According to this world daily reported,The major breakthrough in Boston, and at the American advanced science association(AAAS)Published at the annual meeting of the,And 3 d animation mode for the scholars see the whole arrhythmias pathological causes.


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