摆脱假牙可以靠牙龈了 Get rid of the false teeth can rely on the gums

　　英科学家用牙龈细胞和鼠细胞培育出新牙 British scientists to cultivate new tooth gum cells and mouse cells

　　据英国媒体3月9日报道，英国伦敦国王学院的研究人员提取成人牙龈组织细胞，将其与取自老鼠的另一种细胞结合，成功培育出一颗新牙。他们表示，将来某一天，牙医有可能为缺牙患者换上这种新牙齿。

According to British media reported on March 9,King's college London researchers extracted adult periodontal tissue cells,It combines with another kind of cells taken from mice,Successfully developed a new tooth.They said,One day in the future,Dentists may for patients with this kind of new teeth missing.

　　在最新的研究中，他们从成人患者的牙龈中提取上皮细胞，在实验室里大量培养，再将它们与老鼠的间质细胞混合。这种间质细胞被培养出“诱导作用”——“指示”上皮细胞开始发育成为牙齿。研究人员把这种细胞混合物移植到老鼠身上，结果长出拥有成活根部的人鼠混合牙。

In the latest study,They extracted from adult patients with gingival epithelial cells,Mass culture in the laboratory,Then mix them with the mouse mesenchymal cells.The mesenchymal cells were produced"entrainment"--"instructions"Epithelial cells begin to develop into the teeth.The researchers call this mixture of cells transplanted into the mice,Results grow with survival rat hybrid tooth roots.

　　研究人员表示，下一步将是找到可轻易获取的人类间质细胞资源，并培养出足够的细胞，使之成为能够应用于临床的有效技术。

The researchers said,The next step will be to find human mesenchymal cells can easily access to resources,And produce enough cells,Make it become the effective technology can be applied to clinical.

　　据研究团队负责人保罗·夏普教授透露，他们可以在智齿的牙髓中找到所需的间质细胞，但是可获得的量很有限。现在要做的是寻找获取间质细胞的简单方法。“而下一个主要挑战是研究将成人间质细胞培养成为牙齿诱导物的方法，现在，我们只能利用胚胎间质细胞做到这一点。”

According to professor Paul sharp, head of the team,They can be found in wisdom tooth pulp mesenchymal cells as needed,But the available quantity is limited.Have to do now is to find simple way to gain the mesenchymal cells."The next major challenge is the research will be a mass cell culture become teeth inducer,now,We can only use embryonic mesenchyme cells to do this."

　　他还称，希望这种技术将来可以取代目前使用的无法复制自然牙根结构的种植牙。不过，要达到这个目的，它的价格必须类似于种植牙，因此要找到简单而廉价的方法。

He also said that,Hope that this technology can replace the current use in the future can't replicate natural root structure of dental implants.but,To achieve this goal,The price must be similar to the dental implants,So to find a simple and cheap method.

　　卡迪夫大学骨生物学与组织工程学专家阿拉斯泰尔·斯隆教授表示，这项工作意义重大，也是令人兴奋的进步；目前这类研究对临床的最大影响是牙齿生物填料的研发，在未来10至15年内，该技术有望得到部分应用。

Bone biology and tissue engineering at Cardiff university expert professor Alastair Sloan said,This work is of great significance,And exciting progress;At present this kind of research is the biggest influence on clinical dental research and development of biological packing,In the next 10 to 15 years,The technology is expected to get part of the application.

　　据中国日报

According to China Daily