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山东今年54名患者注射克林霉素出现不良反应--亲民维稳网络舆情监测室
2012-08-24

  

注射克林霉素54患者“受伤” Injection clindamycin 54 patients“injury”

  

(山东)省药品不良反应监测中心提醒,老人儿童及肾功能低下患者慎用 (shandong)Province adverse drug reaction monitoring center warned,The old man children and renal function in patients with low used

  23日,省药品不良反应监测中心发布《山东省药品不良反应监测信息》,提醒注意克林霉素注射剂的肾脏损害风险。在该中心2012年的药品不良反应数据库中,克林霉素注射剂静脉滴注给药引起血尿、肾功能损害等不良反应54例。

23,Province adverse drug reaction monitoring center issued《Shandong province adverse drug reaction monitoring information》,Reminding clindamycin injection of kidney damage risk。In the center of the 2012 adverse drug reaction in the database,Clindamycin injection intravenous drip to medicine cause hematuria、Renal impairment of 54 cases of adverse reactions such as。

  山东省药品不良反应监测中心副主任田月洁介绍,从监测数据来看,克林霉素注射剂引起不良反应的数量较多,应引起足够重视。“在今年的药品不良反应数据库中,克林霉素注射剂静脉滴注给药引起血尿、肾功能损害等不良反应达54例,庆幸的是,这些患者经治疗后都痊愈了。”

Shandong province adverse drug reaction monitoring center, deputy director of the clean on field is introduced,From the monitoring data to see,Clindamycin injection adverse reaction caused by large number of,Should cause enough attention。“In this year's adverse drug reaction in the database,Clindamycin injection intravenous drip to medicine cause hematuria、Kidney damage and other adverse reaction of 54 cases,The good news is,These patients all recovered after treatment。”

  据介绍,克林霉素又称氯洁霉素,是常用的抗菌药物,注射剂包括盐酸克林霉素注射剂和克林霉素磷酸酯注射剂,临床有肌肉注射或静脉滴注给药两种给药途径。分析表明,肾损害是克林霉素的已知不良反应,此类不良反应在大剂量、高浓度、快速滴注时,发生风险的几率则大大增加。

According to introducing,Clindamycin also called chloride lincomycin,Is a common antibacterial drugs,Injection including hydrochloric acid clindamycin injection and clindamycin phosphate injection,Clinical have intramuscular injection or intravenous drip to medicine two route of administration。Analysis shows that the,Renal damage is clindamycin of known adverse reaction,Such adverse reaction in large doses、High concentration、Quick drip when,Happen risk probability is greatly increased。

  该中心提醒,在临床用药时,应控制给药剂量和稀释浓度,分次、缓慢给药,在出现腰痛、血尿等肾损害的前期症状时,应暂停用药,必要时进行相关检查。对于老人、儿童以及肾功能低下患者,则应格外谨慎,小于4周的婴儿则不能使用。该中心同时建议研究机构和生产企业对其肾损害的剂量进行深入研究,采取更加有效的方法,减少肾损害的发生。

The center warned,In the clinical application,Should be controlled drug dose and diluted concentration,Points times、Slow to medicine,In case of lumbago、Hematuria and renal damage when early symptoms,Should suspend drug,Necessary relevant inspection。For old people、Children and renal function in patients with low,It should be particularly cautious,Less than 4 weeks of baby, can't use。The center also recommended that research institutions and production enterprise on the renal damage dose for in-depth study,Adopt more effective method,To reduce the occurrence of renal damage。

  据悉,目前我省已建立了省、市、县三级药品不良反应监测机构,实现了对药品不良反应的全面监测。通过对所收集信息的及时分析和评价,快速发现药品风险,及时采取控制措施,防止危害蔓延。(记者 李钢)

It is reported,At present our province has established the province、city、County level 3 adverse drug reaction monitoring mechanism,Realize the comprehensive monitoring adverse drug reaction。Based on the information collected timely analysis and evaluation,Quickly find that drug risk,Take timely control measures,Prevent harm from spreading。(Reporter LiGang)


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