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异体移植猪供体培育启动:借猪胰岛救治糖尿病患--亲稳网络舆情监测室
2012-09-03
把我的胰岛,奉献给糖尿病人 Put my islet,Dedicated to people with diabetes
一头猪的价值再发现 The value of a pig again found
为什么在器官移植上,不是黑猩猩这个与人类基因有98.8%相似性的灵长类动物,而是一头猪,最终担负起拯救人类的使命?
Why in organ transplantation,Not the chimpanzee this and human gene 98.8% similarity primates,But a pig,Finally take on the mission to save humanity?
在只有1%同种供体的困境下,“异种一号”带给糖尿病人什么样的希望?
In only 1% of the same donor crisis,"Species number one"People with diabetes to what kind of hope?
这些“家世传奇”,具有自主知识产权的供体猪,活在怎样一种被严密监控的“幸福生活”中?
these"Family legend",With independent intellectual property rights of the donor pig,How to live in a be closely monitored"Happy life"in?
在等待中死去 In waiting to die
林肯和乔丹一直以为,他们生活在一个与世隔绝的社区里。
Lincoln and Michael Jordan thought,They live in an isolated communities.
科学家说,他们是地球最后一批存活的人类。在他们这个群体里面,将会抽签决定人选,派去一个世外桃源般的小岛生活。但在没选中之前,他们要忍受没有自由、备受监管的生活。
Scientists say,They are the earth the last batch of the human survival.This group in their inside,Will draw lots candidate,Sent to a xanadu of island life.But not checked in before,They will bear no freedom/The supervision of life.
当林肯和乔丹“幸运”当选后,他们发现了一个惊人秘密——原来所谓的世外桃源根本不存在,他们只是一群被定制的克隆人。他们前往小岛,面对的不是美丽生活,而是要掏出他们鲜活的器官,用以拯救人类——那些身患重症的亿万富翁,或是政界大佬。
When Lincoln and Michael Jordan"lucky"After he was elected,They found a surprising secret - formerly so-called xanadu doesn't exist,They are just a group of be customized clone.They went to the island,In the face of not beautiful life,But to take out their fresh organ,To save human -- those with severe billionaire,Or two political.
这是《变形金刚》导演迈克尔·贝执导的又一部科幻大片《逃出克隆岛》的剧情。豆瓣网友评论,迈克尔·贝把一部大俗片拍出了深度——它反映了人类的纠结与矛盾:对于那些急需一颗健康的肾脏或是心脏来拯救性命的人而言,克隆技术却始终面临着伦理拷问而备受争议。那些饱受肾病、肝病、糖尿病折磨的患者,他们的出路在哪?
This is[transformers]Director Michael bay and directed a science fiction blockbuster[The island]plot.Gae the net friend comment on,Michael bay put a big common tablet made a depth - it reflects human entanglements and contradiction:For those who need a healthy kidney or heart to save the life of the people,Cloning technology has always faced with ethical torture and controversial.Those who suffered from kidney disease/Liver disease/Diabetes patients with torture,Their way out?
8月18日,这一问题在中国有了一个可以运用到临床的求解方式,“解药”来自于一头猪——“异种一号”体内的胰岛细胞。
August 18,,This problem in China have a can be applied to clinical solving ways,"antidote"From a pig --"Species number one"The body of the islet cell.
当天,中南大学湘雅三医院对外表示,世界第二家异体移植猪供体培育及胰岛研发中心正式启动。把它转换成通俗语言就是说,把猪身上的胰岛细胞移植到糖尿病人身上,让糖尿病人重获新生。
The day,Central south university xiangya hospital three foreign said,The world's second home allograft pig donor cultivation and islet r&d center official start.Convert it to popular language means,The pigs islet cell transplantation to diabetic person,Let people with diabetes regain a new life.
作为国内少有的糖尿病异种移植治疗研究者,王维从1995年开始,在湘雅三医院10万元资金支持下,建立胰岛移植实验室,启动胰岛移植前期研究。
As the domestic rare diabetes xenograft therapy researchers,Wang since 1995,Xiangya hospital in three 100000 yuan capital support,Establish islet transplantation laboratory,Start the islet transplantation research.
“每10个中国人,就有一个糖尿病人。”王维列举了一组数字:中国目前有9000万成年糖尿病患者,加上儿童共有1亿多糖尿病患者,其中4000万患者胰岛功能衰竭,需要进行胰岛移植手术,但供体的极度短缺,令许多患者希望渺茫。
"Every 10 Chinese,There is a people with diabetes."Wang wei set forth a series of Numbers:China now has 90 million adult patients with diabetes,With more than 100 million children patients with diabetes,Including 40 million patients of islet function failure,The need for islet transplantation surgery,But donor extreme shortage,Make many patients hope is frail.
这是所有器官移植面临的共同问题。“目前可能只有1%的供体,根本无法解决4000万胰岛功能衰竭病人的需要。”王维说。
This is all the organ transplant face a common problem."At present may only 1% of the donor,Can't solve 40 million islet function failure the patient's need."Wang wei said.
2000年,湘雅三医院首获国家自然科学基金课题,开展经肝动脉肝内移植猪胰岛细胞治疗糖尿病动物实验研究,2001年被批准展开临床研究。
In 2000,,Three xiangya hospital first by the national natural science fund project,To carry out the hepatic artery intrahepatic transplantation ZhuYiDao cells in the treatment of diabetes animal experimental study,In 2001, he was approved to expansion clinical research.
2000年-2004年,湘雅三医院先后为22名患者进行了异种胰岛细胞的移植,这些“猪——人”胰岛移植的糖尿病患者中,20例患者有效,其中6例疗效显著。2011年底,王维课题组对这22例患者进行了复查,无一例出现严重不良反应和明显并发症。
In 2000-2004,Three xiangya hospital successively for 22 patients underwent species islet cell transplantation,these"Pig - people"Islet transplantation in patients with diabetes,20 patients were effective,Six cases of curative effect is distinct.By the end of 2011,Han wang wei to the 22 patients were review,No case of severe adverse reactions and obvious complications.
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