中新社武汉9月12日电 (蒋明)武汉大学基础医学院12日披露，该院科研人员发现一种名为“表达CD56分子的T淋巴细胞”具有抗艾滋病毒感染的作用。这项科研成果发表在8月的国际著名学术刊物《淋巴细胞生物学》杂志上。

China news agency on September 12, wuhan (JiangMing)Wuhan university foundation medical school 12 disclosure,Hospital researchers found a name"Express CD56 molecular T lymphocyte"It can resist the effect of HIV infection.The research results published in the August international famous academic publications[T cell biology]magazine.

　　这项研究由该院教授侯炜博士和武汉大学动物实验中心科研人员合作完成。据侯炜介绍，这种名为“表达CD56分子的T淋巴细胞”，是一类“桥梁细胞”，它既具有自然杀伤的功能，又能起到自我保护的功能。它是人类天然免疫系统的一个重要组成部分，在外周血单核细胞中占5%至15%，而肠道和肝脏中50%的免疫细胞为这种细胞。

The study by the hospital of wuhan university professor dr HouHui and animal experiment center researchers collaboration.According to HouHui introduced,This name"Express CD56 molecular T lymphocyte",Is a kind of"Bridge cell",It has both the function of natural killer,And can play the function of self protection.It is human natural immune system is an important part,In the peripheral blood mononuclear cells 5% to 15%,And 50% of intestinal and liver of immune cells for this cell.

　　武汉大学专家说，这种细胞以前研究往往只被发现在抗肿瘤和抗肝炎病毒感染中起到作用，而没有发现它在抗艾滋病毒感染上有较强作用。

Wuhan university, experts say,This kind of cell research often before only was found in antitumor and anti hepatitis virus infection plays a role,But didn't find it in the anti HIV infected with a strong role.

　　历经3年多，侯炜和武汉大学动物实验中心霍文哲教授团队，首次发现这种“表达CD56分子的T淋巴细胞”培养液中的分泌物可以抑制艾滋病毒的感染和复制，并且这种活性具有广谱性，既可抑制实验室保存的艾滋病毒病毒株，也可抑制临床上分离得到的艾滋病毒病毒株。

After three years,HouHui and wuhan university animal experiment center HuoWenZhe professor team,First found that the"Express CD56 molecular T lymphocyte"Nutrient solution of secretion can inhibit infection with the AIDS virus and copy,And this kind of activity have a broad spectrum of sex,Can inhibit laboratory saved the AIDS virus strains,Also can inhibit clinically separation get AIDS virus strains.

　　该研究团队还发现，虽然这种细胞培养液中的分泌物对艾滋病毒进入细胞的协同受体影响甚微，但其分泌物可增强干扰素调节因子的作用，从而引起巨噬细胞发挥作用，“抗击”艾滋病毒。此外，“表达CD56分子的T淋巴细胞”具有增强细胞内一种新发现的抗艾滋病毒的细胞因子的作用。(完)

The team also found,Although this kind of cell culture solution of secretion of the AIDS virus into the cells' cooperative receptor has little effect,But its secretion can enhance the effect of interferon regulatory factor,Thus cause macrophages play a role,"fight"HIV.In addition,"Express CD56 molecular T lymphocyte"It has the enhancement cell inside a new discovery of anti-hiv cytokine role.(finish)