中新社上海10月13日电 (记者 陈静)中国是世界上胃癌多发国，且近年来发病率明显攀升。中国第一个能明显降低HER2阳性晚期胃癌患者死亡风险、提高总生存期的靶向药物13日正式上市。对此类胃癌患者而言，这意味着其死亡风险将降低35%，生存期或将超过1年。

China news agency Shanghai on October 13 (Reuters) (Reporter reiter)China is the world's stomach multiple countries,And in recent years the incidence rate rise significantly.China's first can obviously reduce the HER2 positive in patients with advanced gastric cancer risk of death/Improve the total life cycle of targeted drugs 13 officially listed.For this type of gastric cancer in patients,This means that the risk of death would be reduced by 35%,Survival period or more than one year.

　　有研究称，中国、韩国和日本胃癌患者总数占全球患者总数的2/3。近年来，随着环境、饮食结构等因素的变化，中国胃癌发病率明显攀升，在一些经济发达城市尤为明显。

A study said,China/South Korea and Japan the total number of patients with gastric cancer patients with two-thirds of the global total.In recent years,As environmental/The change of such factors as diet,China's stomach cancer incidence obviously rise,In some developed city is especially obvious.

　　中国临床肿瘤学会主席、解放军八一医院副院长秦叔逵告诉记者，胃癌因早起隐匿性强，约七成患者确诊时即为中晚期。由于缺乏有效治疗手段，胃癌整体治疗效果并不理想，患者5年存活期在5%至20%左右，总体平均生存时间小于1年。

Chinese clinical cancer society President/The people's liberation army August first vice President of the hospital QinShuKui told reporters,Gastric cancer because the early strong stealthiness,About seventy percent of patients diagnosed as the mid and late stage.Due to the lack of effective treatment means,Gastric cancer overall treatment effect is not ideal,Patients 5 years survival time in the 5% to 20%,The overall average survival time less than 1 year.

　　HER2是人表皮生长因子受体—2的缩写。正常细胞内，HER2将生长信号从细胞外传递至细胞内，通过信号传导促进细胞进行生长和分裂。如果癌症患者为HER2阳性，则表示患者癌细胞有过多HER2蛋白出现在癌细胞表面，会刺激细胞疯长，此类病患病情易复发和转移，预后较差。据了解，上海罗氏制药研制的HER2类药物此前曾成功运用于HER2阳性乳腺癌治疗。

HER2 is epidermal growth factor receptor - the abbreviation of 2.Normal cells,HER2 will grow signal from extracellular communicated to the cells,Through the signal conduction promote cells growth and division.If cancer patients for HER2 positive,It means patients cancer cells have too many HER2 protein appeared in cancer cell surface,Can stimulate cell overgrowth,Such patients condition easy relapse and metastasis,Prognosis is poor.It is understood,Shanghai roche pharmaceuticals developed HER2 drugs had successfully used by positive HER2 breast cancer treatment.

　　今年8月，HER2药物——赫赛汀联合化疗正式被中国国家市药监局批准用于HER2阳性晚期胃癌的一线治疗。中国胃癌治疗进入分子靶向时代。

August,HER2 medication - Hector the combination chemotherapy statins officially by the Chinese national city administration for advanced gastric cancer positive HER2 a line treatment.China's stomach cancer treatment into the molecular targeted era.