对于我国1.6亿高血压患者，如何选择安全的降压药来控制好血压，的确是一个难题。中日友好医院中西医结合心脏内科主任、主任医师黄力说，降压效果好，能使血压维持在正常水平；24小时平稳降压，避免一天中血压忽高忽低；安全性好，长期服用无肝肾毒性；没有药物的相互作用，便于联合用药，是选择降压药的四大原则。

For the 160 million hypertension patients in our country,How to choose the safety of blood pressure medication to control blood pressure,Is really a problem.China-japan friendship hospital, combine traditional Chinese and western medicine medical director of the heart/Chief physician Huang Li said,Antihypertensive effect is good,Can make blood pressure maintained in the normal level;Smooth step-down 24 hours a day,Avoid the high and low blood pressure in a day;Good safety,Long-term use of hepatorenal toxicity;No drug interactions,Is advantageous for the combination,Are the four principles of anti-hypertension drugs.

　　“为什么要强调24小时平稳降压？因为血压如果降得过快，患者会出现头痛、头晕、心慌等症状。”黄力说，高血压患者常有晨间血压波动，早晨4点-6点为事件高发时段。晨间血压急剧升高或长期降压不平稳会诱发中风、心肌梗死等心脑血管急症。

"Why emphasize smooth step-down 24 hours?Because if blood pressure drop too fast,Having a headache patients/dizzy/The symptom such as palpitate."Huang Li said,Patients with high blood pressure often morning blood pressure fluctuations,4-6 in the morning peak time for events.Morning blood pressure rise sharply or long-term step-down can cause the stroke is not smooth/Myocardial infarction and other cardiovascular emergency.

　　“半衰期至少长达24小时的降压药，每天只需服用1次，避免多次服药造成血压忽高忽低；且1次服药不容易忘记，避免漏服引起血压波动；即使偶尔漏服，药效可以维持更长时间。这类降压药才是24小时维持平稳疗效的降压药。”黄力说。

"Half-life of at least 24 hours blood pressure medication,Just take one a day,Avoid multiple drugs cause high and low blood pressure;And one drug is not easy to forget,To avoid missing cause fluctuations in blood pressure;Even if occasionally missing,Effectiveness can be maintained for a longer time.This kind of blood pressure medication is 24 hours to maintain stable curative effect of blood pressure medication."Huang Li said.

　　有些患者在血压降下来后就想停药，黄力说，这样并不可取。除了某些轻度高血压停药后可以维持正常血压，其他高血压都不适宜停药。“长期服用降压药，可以保护心、脑、肾等重要脏器，减少不良事件发生，降低死亡率。如果血压降至理想水平，可在医生指导下逐步减少药物剂量和种类。”（记者潘波）

Some patients after the blood pressure down to drug withdrawal,Huang Li said,This is not an option.In addition to some minor after discontinuation of high blood pressure can maintain normal blood pressure,High blood pressure are not suitable for other drug withdrawal."Long-term use of antihypertensive agents,Can protect the heart/The brain/The kidney, and other important organs,Reduce adverse events,Reduce mortality.If blood pressure drop to an ideal level,Can be under the guidance of gradually reduce drug dosage and types."(The reporter Pan Bo)