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甘肃发现5个人类新HLA等位基因 对研究遗传意义重要--亲稳网络舆情监控室
2013-03-12

  中新网兰州3月12日电 (史静静)甘肃省血液中心12日提供消息称,今年该中心新发现的5个人类新HLA等位基因,日前得到了世界卫生组织的认可,并分别给予命名。同时,基因序列被正式收录至GenBank美国国立卫生研究院维护的基因序列数据库。

Beijing, lanzhou, March 12 (Reuters) (Shi Jingjing)Gansu province blood center 12 provides message said,This year, the center of the newly discovered five human new HLA allele,Has been recognised by the world health organization (who),And given names respectively.At the same time,Gene sequences have been officially accepted to GenBank database of gene sequences at the national institutes of health maintenance.

  HLA即人类白细胞抗原,是个体的“基因身份证”,是人类最复杂的遗传多态性系统。HLA在骨髓移植中发挥着重要作用,其是否匹配决定着移植的成败。

HLA is human leucocyte antigen,Is an individual"Gene id card",Is the most complicated human genetic polymorphisms of system.HLA plays an important role in the bone marrow transplant,Whether the matching determines the success or failure of transplantation.

  此外,HLA还被广泛用于亲子鉴定、法医学鉴定以及输血医学等方面的研究。

In addition,HLA has been widely used in paternity test/Forensic medicine appraisal as well as in blood transfusion medicine research.

  甘肃省红十字血液中心输血研究所副所长李国英介绍,此次新发现的5个人类新HLA(人类白细胞组织相容性抗原)等位基因,分别正式命名为A﹡11:141;A﹡24:231;A﹡68:100;B﹡15:271;B﹡27:103。

Gansu province Red Cross blood center deputy director of the institute of blood transfusion to introduce Mr Li,The newly discovered five new human HLA(Human leukocyte histocompatibility antigens)allele,Formally named as A left, and 1 respectively;A left, he took one;A left, 68:68;B, left, and 1;Left, will 3 B.

  “同时发现5个新HLA等位基因,在全国的研究中比较少见。”李国英说,这次多个HLA等位基因的发现,不仅为人类遗传基因库增添了新“成员”,对研究中国人群的“遗传秘密”具有重要意义。(完)

"At the same time find five new HLA allele,In national studies are relatively rare."Mr Li said,The number of HLA alleles found,Added new not only for human genetic gene pool"Members of the",To the study of population in China"Genetic secrets"It is of great significance.(After the)


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