14日是第八个“世界肾脏病日”，今年的主题是“防治急性肾损伤”。在我国，每年有近400万人患急性肾病，而药物的不规范使用已成为导致急性肾损伤的重要原因。据中医大一院肾病科主任宋立群介绍，约20%～34%的急性肾功能衰竭与应用肾毒性药物有关。

14 is the eighth"World kidney day",This year's theme is"Prevention and treatment of acute kidney injury".In our country,Each year, nearly 4 million people suffering from acute kidney disease,Non-standard and drug use has become an important cause of acute kidney injury.According to the director of college of traditional Chinese medicine hospital ShenBingKe Song Liqun is introduced,About 20% ~ 34% of acute renal failure is associated with nephrotoxicity drugs application.

五种抗生素要当心 Five kinds of antibiotic should be careful

　　1、氨基糖苷类：如庆大霉素、丁胺卡那霉素、链霉素、新霉素等，其中以新霉素、卡那霉素，庆大霉素毒性作用最强。

1/aminoglycoside:Such as gentamicin/amikacin/streptomycin/Neomycin, etc.,Among them with neomycin/kanamycin,Gentamicin strongest toxic effects.

　　2、青霉素类：各种半合成青霉素均可诱发肾脏损害。

2/Penicillin class:All kinds of semi-synthetic penicillin can cause kidney damage.

　　3、头孢霉素类：以第一代头孢霉素最明显。

3/Cephalosporins drug classes:With the first generation cephalosporin drug is the most obvious.

　　4、四环素族：可以增加蛋白分解加重氮质血症

4/Tetracycline family of:Can increase the decomposition of protein increase nitrogen qualitative hematic disease

　　5、万古霉素以及磺胺类药物也可导致肾损害。

5/Vancomycin and sulfa drugs can also cause kidney damage.

阿司匹林等抗炎药要慎用 To be cautious with aspirin and other anti-inflammatory drugs

　　除了抗生素外，非甾体类抗炎药物导致的肾损害也比较常见，包括阿司匹林、布洛芬(安瑞克)、保泰松、萘普生、吲哚美辛(消炎痛)等。此外，X线造影剂、抗肿瘤药物如顺铂、氨甲蝶呤、利尿剂等应用不当也可导致肾损害。

In addition to antibiotics,Nonsteroidal anti-inflammatory drugs cause renal damage is also common,Including aspirin/ibuprofen(AnRuiKe)/bute/naproxen/indomethacin(indomethacin), etc..In addition,X-ray contrast agents/Antitumor drugs such as cisplatin/methotrexate/Improper application such as diuretics also can lead to kidney damage.

滥用中药也能中毒 Abuse of traditional Chinese medicine can also be poisoning

　　临床上，有一些中药本身具有毒性，主要有马兜铃、木通、防己、厚朴、细辛等，需在医师和药师的指导下使用。患者一旦滥用上述中药，很容易导致药物性肾损伤，严重的可致急性肾衰竭。

The clinical,Have some Chinese medicine itself has toxicity,Mainly include the aristolochia/Akebia stem/The f/hopu/Asarum, etc.,Need to be used under the guidance of physicians and pharmacists.Once a patient abuse of the traditional Chinese medicine,Easily lead to drug-induced renal injury,Serious can cause acute renal failure.

　　宋立群特别提醒，市民应用抗生素时应注意避免长时间用药，如氨基甙类抗生素连续应用不应超过10天；避免与肾毒性有协同作用的药物合用，如氨基甙类抗生素不应与先锋霉素(Ⅳ、Ⅴ 、Ⅵ)合用；避免与强利尿剂合用，防止循环血容量不足，加重抗生素的肾毒性作用；用药时注意监护肾功能，定时检查尿液，早期发现药物性肾损害。记者 霍营

Song Liqun special remind,People use of antibiotics should be paid attention to avoid long time use,Continuous use of antibiotics such as amino glycosides should not exceed 10 days;Avoid medicines have synergies with renal toxicity,Such as amino glycoside antibiotics should not be and cephalothin(Ⅳ/Ⅴ /Ⅵ)pooling;To avoid strong diuretic share,To prevent the circulation blood volume is insufficient,Increased renal toxic effects of antibiotics;When medicine pay attention to the monitoring of renal function,Regularly check the urine,The early detection of drug-induced renal damage.The reporter HuoYing