脑深部电刺激术示意图

Deep brain electrical stimulation

    当前，帕金森病已成为继肿瘤、心脑血管病之后中老年人的“第三杀手”。全球约有400万帕金森病患者，其中超过200万人在中国。随着人口老龄化的加剧，帕金森病患者的数量也越来越多。加上由于环境因素、遗传因素、年龄因素及长期精神压力等，该病也有年轻化的趋势。

    The current,Parkinson's disease has become the tumor/After cardio-cerebrovascular disease in the elderly"The third killer".About 4 million Parkinson's patients around the world,More than 2 million people in China.With the aging of the population increases,The number of Parkinson's disease is also more and more.And due to environmental factors/Genetic factors/Age factors and long-term mental stress, etc,The disease also have a younger trend.

    抖动、僵硬、迟缓是帕金森病典型的几个表现，但因为帕金森是一个综合征，是很多症状的集合体，因此，不是只有单一症状，抖动只是它最典型的一个症状，还有大概1/3患者不出震颤，而表现出非常明显的僵硬和迟缓。

    jitter/stiff/Slow is typical of Parkinson's disease a few,But because of Parkinson's disease is a syndrome,Is an aggregate of many symptoms,so,Not only a single symptom,Jitter is one of the most typical symptoms,And about 1/3 patients tremor,And showed very obvious rigid and slow.

    对于帕金森病的治疗，明确诊断第一步，药物治疗是第二步，药物治疗之后才是手术治疗。手术是一个最新兴的治疗方式，也代表着人类科学技术发展的最高水平。目前，脑深部电刺激术是治疗帕金森病唯一安全有效的外科疗法。

    In the treatment of Parkinson's disease,The first step in diagnosis,Drug therapy is the second step,After drug treatment is surgery.Surgery is one of the most emerging treatments,Also represents the highest level of development of human science and technology.At present,Deep brain stimulation surgery is the only safe and effective surgical treatment of Parkinson's disease therapy.

    脑深部电刺激术俗称脑起搏器，是帕金森病外科治疗领域里程碑式的新技术。它可以有效地改善帕金森病的主要症状，提高患者的生活质量。

    Deep brain stimulation surgery known as brain pacemaker,Is a milestone in the field of surgical treatment for Parkinson's disease is a new technology.It can effectively improve the main symptoms of Parkinson's disease,Improve the patient's quality of life.

    脑起搏器通过植入大脑中的电极，发放电脉冲至控制运动的相关神经核团，调控异常的神经电活动，从而达到减轻和控制帕金森症状的目的。就像计算机死机后需要重启一样，这个疗法就是要让我们的大脑重新启动。

    Brain pacemaker implanting electrodes in the brain,Electrical pulses to control the movement of the nucleus,Regulating the abnormal neural electrical activity,So as to achieve the aim of reduce and control the symptoms of Parkinson's disease.Just like deadlock after need to restart the computer,This therapy is to make our brain is restarted.

    使用脑起搏器疗法治疗帕金森症具有可逆、可调、安全、微创的特点，可明显改善帕金森患者所产生的动作迟缓/动作失调、肌肉僵直及（或）震颤的症状，也可明显降低服用药物所产生的副作用。绝大部分患者因接受了脑起搏器疗法，运动症状得到全面改善，生活质量提高，能够重返工作岗位；其照料者也可以从繁重的照料工作中解脱出来，创造更多的社会价值。经过逾25年的临床应用，全球已有超过10万名帕金森病患者接受了美敦力脑起搏器手术治疗。在过去10年间，该技术在国内的发展也逐渐成熟；我国已完成超过5000多例，治疗的安全性和有效性得到公认。宣武医院是全世界最大的脑起搏器植入中心，每年有三百多名患者在这里接受手术治疗，目前已完成近2000例，效果良好。

    Use brain pacemaker therapy to treat Parkinson's disease is reversible/adjustable/security/The characteristics of minimally invasive,Can significantly improve patients with Parkinson's disease produced by slow/movement disorders/Muscle rigidity and(or)The symptoms of tremor,Also can obviously reduce the resulting from drug side effects.The vast majority of patients underwent brain pacemaker therapy,And fully improve motor symptoms,The quality of life improve,To be able to return to work;The caregivers can also be free from heavy care work,Create more social value.After more than 25 years of clinical application,Global has more than 100000 Parkinson's patients accepted the medtronic brain pacemaker surgery.In the past ten years,The technology in domestic development also gradually mature;Our country has completed more than 5000 cases,The safety and efficacy of treatment acknowledged.Xuanwu hospital brain pacemaker implanted in the centre is the largest in the world,Every year, more than three hundred patients with surgery treatment here,Currently has completed nearly 2000 cases,Effect is good.

    据2013年世界权威医学杂志《新英格兰杂志》刚刚发表的数据显示，提早进行手术植入起搏器治疗的帕金森患者，无论是生活质量还是运动技能，都有非常大的提高，进而也极大降低了药物的并发症。年龄和疾病病程是选择药物治疗还是手术治疗的重要因素。年龄较轻的患者有更多的生活质量和僵直症状改善，更少的认知并发症以及更为缓慢的中轴症状的恶化，出现药物疗效已明显下降或出现严重的运动波动或异动症，是考虑接受脑起搏器植入的最佳时机。

    According to the world authoritative medical journal in 2013[The New England journal]Just published figures show,Early surgical implant a pacemaker for treatment of patients with Parkinson's disease,Both the quality of life and movement skills,Has a very big enhancement,And also greatly reduced the complications of drug.Age and disease duration is an important factor to choose to drug therapy or surgery.Younger age of the patients have more quality of life and rigidity symptom improvement,Cognition and less complications and more slowly axial symptoms worse,Drug efficacy has obvious decline or severe movement disorder fluctuations or changes,The right time to consider accepting brain pacemaker implantation.

    那么，是所有的患者都适合脑深部电刺激治疗吗？根据2012年发表的《中国帕金森病脑深部电刺激疗法专家共识》，脑深部电刺激疗法的适应症是：原发性帕金森病；服用复方左旋多巴曾经有良好的疗效；疗效已明显下降或出现严重的运动波动或异动症，影响生活质量；排除痴呆和严重的精神疾病。

    then,Is all of the patients suitable for deep brain electrical stimulation treatment?According to the published in 2012[Chinese deep brain electrical stimulation therapy in Parkinson's disease expert consensus],Indications are deep brain electrical stimulation therapy:Idiopathic Parkinson's disease;Taking compound levodopa has good curative effect;Curative effect is markedly reduced or severe movement disorder fluctuations or changes,Affect the quality of life;Dementia and severe mental illness.

    此外,帕金森病是一种老年病，目前还没有办法预防。所以，患病后应从两方面去努力，一是心理方面，不要认为这个病丢人、尴尬、难堪等，患者要放松心情，积极、乐观地面对。这样也能避免影响家人情绪。二是不要拒绝就医。在医生的指导下，需要吃药的时候吃药，需要手术的时候手术，千万不能自己试图去判断病情。

    In addition,Parkinson's disease is a kind of geriatrics,There is no way to prevent.so,Fell ill from two aspects to work on,Is a psychological aspect,Don't think it a shame/embarrassed/Embarrassed, etc.,Patients to relax,positive/Optimism in the face of.It can also avoid the influence family emotions.The second is don't refuse to go to a doctor.Under the guidance of a doctor,Need to take medicine to take medicine,Need surgery operation,Don't try to judge the illness.