枣庄患者张某被确诊为山东首例人感染H7N9禽流感病例后，我市卫生系统高度戒备，今日召开紧急防控会议，确定济南定点医院增加市中心医院，而我市所有发热门诊开始对流感样病例开展初筛，所有二级以上医疗机构的发热门诊，均有甲型流感病毒抗原检测试剂，可以第一时间进行筛查。

Zhang was confirmed as shandong zaozhuang patients case of human infection with H7N9 after bird flu cases,The city health system on high alert,Today for a meeting of the emergency prevention and control,Increased to determine fixed-point hospital of jinan central hospital,And the city all fever clinics start of influenza-like cases to carry out the initial screen,Above all the secondary fever outpatient medical institutions,Have the swine flu virus antigen detection reagent,Screening can be the first time.

　　据市卫生局党委书记、局长贾堂宏介绍，从全国来看，目前疫情走势趋缓，上海已经4天没有新发病例报告；北京在出现一例确诊病例后，疫情没有大的变化。但从省内来讲，随着枣庄出现人感染H7N9禽流感确诊病例，我省和济南市的防控形势要严峻得多。

Party secretary of the city health bureau/Director Jia Tanghong is introduced,nationally,The current outbreaks moves to slow,Shanghai has been 4 days no new cases of the report;Following case of confirmed cases in Beijing,Epidemic without big changes.But in the province,Zaozhuang as H7N9 confirmed cases of bird flu infection in people,The prevention and control of the situation in our province and jinan is much more serious.

　　贾堂宏表示，目前济南市疾控中心已将甲型流感病毒抗原检测试剂盒，发到了全市所有设在二级以上医疗机构的发热门诊。根据最新调整的防控策略，市卫生局要求发热门诊先对流感样病例进行初筛，此前该工作由疾控部门负责。据介绍，发热门诊发现流感样病例后，会首先采样让自己医院的化验科做初筛，判断是甲型流感还是乙型流感。“一般半小时之内就能出结果。如果确定是甲型流感，病人样本再送济南市疾控中心病毒实验室进行检测。”市疾控相关人士介绍，这样可以提高检测效率，避免检测资源浪费。

Jia Tanghong said,Now jinan centers for disease control and prevention has a/h1n1 flu virus antigen detection kit,Send to all in the city is located in the second class above fever outpatient medical institutions.According to the latest adjustment control strategy,Municipal bureau of health claims fever clinics first for early screening of influenza-like cases,After the work shall be the responsibility of the department for disease control.According to introducing,Fever clinics after the found of influenza-like cases,Can let oneself first sampling tests of hospital do the initial screening,Judgment is influenza a or b."Generally within half an hour can result.If it is determined a/h1n1 flu,Patient samples and then send virus of jinan city CDC laboratory for testing."Relevant personage introduces city CDC,So that we can improve the detection efficiency,To avoid resource waste.

　　济南市最早确定的人感染H7N9禽流感定点救治医院是市传染病医院。据院长牟壮博介绍，医院从人员到设备均已做好了收治病人的准备；为加强对重症病人的有效治疗，该院也与省立医院、齐鲁医院、省胸科医院的专家建立了密切联系；医院专门救治此类病人的负压病房也将在15天内建成。

Jinan first person infection H7N9 bird flu fixed-point hospital treatment is city infectious diseases hospital.According to dean MouZhuang bo is introduced,Hospital staff to equipment have been prepared to the patients in our hospital;To strengthen the effective treatment of critically ill patients,The hospital was with provincial hospital/Qilu hospital/Provincial thoracic hospital experts has established the close contact;Negative-pressure ward of the hospital special treatment for such patients also will be completed in 15 days.

　　此次会议上，市卫生局宣布，济南市中心医院为我市第二家收治人感染H7N9禽流感病例的定点医院。

The conference,City health bureau announced,Jinan central hospital for zhuhai second people H7N9 bird flu cases in our hospital designated hospitals.

　　我国科学家率先揭示H7N9病毒来源

The scientists were the first to reveal H7N9 virus source in our country

　　新华社北京4月23日电(记者 董峻)

Xinhua Beijing, April 23 (Reuters)(The reporter Dong Jun)

　　中国农业科学院23日发布消息，该院哈尔滨兽医研究所的最新研究表明，在我国导致人感染的新型H7N9流感病毒与同一时期存在于活禽市场上的H7N9禽流感病毒高度同源，在国际上首次从病原学角度揭示了新型H7N9流感病毒的来源。

The Chinese academy of agricultural sciences released on the 23rd,Hospital of Harbin veterinary research institute, according to new research,In our country, the cause of human infection with the new H7N9 influenza virus with the same period exists in live poultry market H7N9 highly homologous avian influenza virus,First in the world from the perspective of etiology reveals the source of new H7N9 influenza virus.

　　研究结果表明，新型H7N9流感病毒是不同来源病毒的重组病毒，它的6个内部基因来源于H9N2禽流感病毒，而血凝素(HA)和神经氨酸酶(NA)基因的来源尚不明确。研究发现，新型H7N9病毒的受体结合位点获得了部分人流感病毒特征的突变，病毒在感染人后获得了关键氨基酸位点的适应性突变，这些可能与该病毒对人的感染和致死能力有关。

Research results show that,New H7N9 flu virus is different sources virus recombinant virus,Its six internal genes from H9N2 avian influenza virus,The hemagglutinin(The HA)And neuraminidase(NA)The source of the genes is unclear.Studies have found that,New H7N9 virus receptor binding sites for some of the characteristics of human influenza virus mutation,After the virus in infected people obtained the key amino acid sites of adaptive mutation,These may be linked to the virus infection and death related to people.

　　哈尔滨兽医所国家禽流感参考实验室主任陈化兰研究员、李呈军研究员带领研究团队先后在上海、安徽的活禽市场和养殖场采集病原学样品970份，在分离自活禽市场采集的样品中检测出20份H7N9禽流感病毒阳性，而所有养殖场样品的检测结果均为阴性。通过基因序列分析表明，H7N9禽流感病毒的各个基因片段与H7N9人体分离株高度同源，证明导致人感染和致死的H7N9流感病毒可能来源于同一时期家禽中的H7N9禽流感病毒。

Harbin veterinary researcher Chen, director of the national avian influenza reference laboratory/Li army researchers led the research team in Shanghai/Anhui live poultry markets and farms collected samples of etiology, 970,In separation since the acquisition of live poultry market samples detected 20 H7N9 tested positive for avian influenza virus,And all sample test results were negative for farms.By gene sequence analysis,Each H7N9 avian influenza virus gene fragments and H7N9 human isolates is highly homologous,Prove to be lead to infection and death of H7N9 influenza virus may H7N9 avian influenza virus in poultry is derived from the same period.

　　该实验室目前正在积极评估已有储备的H7亚型禽流感病毒疫苗对新型H7N9禽流感病毒的免疫保护效果，同时加紧研制专门针对新型H7N9禽流感病毒的疫苗。陈化兰表示，应进一步加强H7N9禽流感病毒在家禽中的检测，查明病毒的来源和传播途径，并深入开展H7N9病毒在动物模型中的致病性、传播能力及致病机理研究，为制定科学合理的防控措施提供理论依据。

The lab is currently actively evaluating existing stocks of H7 subtype of avian influenza virus vaccine immune protective effect of new H7N9 avian flu virus,Working specifically for new type H7N9 bird flu virus vaccine.Chen said,Should further strengthen H7N9 detection of avian influenza virus in poultry,Find out the source and route of transmission of the virus,In-depth development and H7N9 pathogenicity of virus in animal models/Communication ability and the pathogenesis research,To provide theoretical basis for scientific and reasonable prevention and control measures.

　　我省首次发现H7N9确诊病例

First discovered in our province H7N9 confirmed cases

　　患者目前病情仍较危重

The patient is critically ill

　　本报4月23日讯(记者 白鹏飞李雪梅 通讯员 高晖 郝金刚)山东省卫生厅4月23日发布通报，山东省确诊1例人感染H7N9禽流感病例，患者为枣庄市市中区的张某。

This newspaper on 23 April(The reporter Bai Pengfei Li Xuemei correspondent Gao Hui Hao Jingang)Shandong province health department released on April 23,Shandong province confirmed 1 case of human infection with H7N9 avian influenza,Patients in the downtown district of zaozhuang zhang.

　　据介绍，患者张某，男，36岁，家住枣庄市市中区，从事建材批发工作。患者发热、咳嗽6天、憋喘1天后，于4月21日晚到枣庄市立医院就诊，以“重症肺炎”收治入院。4月22日下午，山东省疾病预防控制中心报告患者的样本检测结果为人感染H7N9禽流感病毒核酸阳性。4月23日，经中国疾病预防控制中心实验室复核为人感染H7N9禽流感病毒核酸阳性。山东省卫生厅专家组依据患者临床表现、实验室检测和流行病学调查结果等，诊断该病例为人感染H7N9禽流感确诊病例。这是我省首次发现的确诊病例。

According to introducing,Patients with zhang,male,36 years old,Who lives in the downtown district of zaozhuang,Work in the building materials wholesale.Patients with fever/Cough for 6 days/Hold back for 1 days,On the evening of April 21 to the appointed hospital of zaozhuang,In order to"Severe pneumonia"admitted.On April 22, afternoon,Shandong center for disease control and prevention reported human infections H7N9 patient samples test result tested positive for avian influenza virus nucleic acid.On April 23,,Review human infections by the Chinese center for disease control and prevention laboratory H7N9 tested positive for avian influenza virus nucleic acid.Shandong province health expert group on the basis of clinical manifestations of patients/Laboratory testing and epidemiological findings,Diagnosis of the cases of human infection H7N9 avian influenza confirmed cases.This is confirmed cases of the first discovered in our province.

　　省卫生厅表示，经医院积极治疗，患者目前病情仍较危重。经医学观察，9名密切接触者未发现异常。

Provincial health department said,The active treatment from the hospital,The patient is critically ill.The medical observation,Nine close contacts no abnormalities are found.