中华医学会泌尿外科学分会候任主任委员、第二军医大学校长孙颖浩教授领衔的研究团队，在世界上首次进行了基于大规模人群和全基因组水平的中国人前列腺癌易感基因筛查研究，并发现2个中国人群特异的易感基因位点。

The Chinese medical association urinary surgery branch of the chairman of the committee president-elect/The second military medical university President professor SunYingHao led research team,For the first time in the world has been made based on large populations and the whole genome level of Chinese prostate cancer susceptibility gene screening study,And found two Chinese population specific susceptibility loci.

　　这一研究成果由9月30日出刊的最新一期国际顶级学术期刊《自然遗传学》发布，它揭示了前列腺癌种族差异的遗传学基础。

The research achievements by September 30, issue the latest issue of top international academic journals[Nature genetics]release,It reveals the prostate cancer ethnic diversity of genetics.

　　前列腺癌发病机制存在十分明显的人种差异。但目前中国有关前列腺癌的诊疗指南中，参考依据有近90%来源于国外。

Prostate cancer pathogenesis existence very obvious racial difference.But at present, the relevant Chinese prostate cancer diagnosis and treatment in the guidelines,Reference basis for nearly 90% come from outside the country.

　　为系统研究中国人群的前列腺风险相关变异，孙颖浩团队联合中外40多家机构的科研人员，收集了4484名前列腺癌患者和8934名健康者进行对照研究，采用全基因组关联分析技术进行检测。通过研究，除证实了在其他祖先群体中报道的几个关联，还发现了前列腺癌的2个新风险相关位点。

For the system study of Chinese population of prostate risk related variation,SunYingHao team joint chinese-foreign more than 40 institutions of scientific research personnel,Collected 4484 men with prostate cancer and 8934 healthy subjects contrast study was carried out,Using genome-wide association analysis technique were detected.Through the research,In addition to confirmed in other ancestors group reported in several association,Also found two new prostate cancer risk related sites.

　　“这些研究结果有助于我们更深入了解中国人前列腺癌发生的遗传学机制，探索前列腺癌风险预测标志物，并为未来前列腺癌的个体化治疗和新药研发提供了坚实的基础。”孙颖浩说。

"These results will help us to further understand the Chinese of aggressive prostate cancer genetics mechanism,Explore the risk of prostate cancer prediction markers,And for the future of the prostate cancer individual treatment and new drug research and development to provide the solid foundation."SunYingHao said.

　　前列腺癌是威胁男性健康最常见肿瘤之一，在发达国家发病率居男性肿瘤首位。随着中国社会人口老龄化，这一疾病发病率近年来明显上升。(胥金章 肖鑫)

Prostate cancer is the most common threat men's health is one of the tumor,In the developed countries in the incidence of male tumor.With China's social an aging population,The disease incidence increased dramatically in recent years.(XuJinZhang XiaoXin)