中新网广州10月24日电 (王华晓雷)记者今日从2012广州乙肝免疫调控专家高峰论坛上获悉，备受关注的治疗性乙肝疫苗取得阶段性突破。来自中华医学研究会肝病委员会广州临床基地的统计数据显示，这种被业内称作“量身定制”的自体细胞回输疗法，联合抗病毒药物，可改写慢性乙肝患者表面抗原不能转阴的历史。

Beijing on October 24, guangzhou (WangHuaXiao ray)Reporters today from 2012 guangzhou hepatitis b immune regulation experts peak BBS about,Much attention has been paid to the treatment of hepatitis b vaccine has made some breakthrough.From the Chinese medicine research institute liver disease committee guangzhou clinical base of the statistical data shows,This is called the industry"customised"From somatic feedback therapy,Joint antiviral drugs,Alterable patients with chronic hepatitis b surface antigen can't turn history.

　　中华医学研究会肝病委员会主任委员杨君教授认为，这标志着抗病毒药与免疫疗法相结合是未来乙肝治疗的方向。治疗性乙肝疫苗疗法是从患者血液中分离出单个核细胞，通过体外特殊培养，使其发育成特异的免疫细胞并大量扩增，同时赋予专杀乙肝病毒的抗原信息，然后将这种免疫细胞回输到乙肝患者体内，成为乙肝病毒的“撒手锏”，这是目前最具应用前景的生物细胞诊疗技术。

The Chinese medicine research association chairman of liver disease committee three-phase professor thinks,This marks the antiviral drug and immune therapy combined with hepatitis b is the direction of the future.Therapeutic hepatitis b vaccine therapy in patients with blood from isolated individual nucleus cell,Through special training in vitro,Make its development into specific immune cells and a large number of amplification,At the same time give ZhuanSha hepatitis b virus antigen information,Then will the immune cells feedback to second liver patient body,Become the hepatitis b virus"One's speciality",This is the most promising biological cells treatment technology.

　　据了解，该疗法也称自体细胞免疫治疗，可成功解决病毒耐药变异和自身免疫受损这两大医学难题。

It is understood,The treatment is also called from somatic cell immune therapy,Can successfully resolved the virus resistance variation and autoimmune damaged the two medical problem.

　　杨教授介绍，治疗性乙肝疫苗疗法可以诱导患者血液中表面抗原浓度的下降，停药后随防三年，这些患者发生表面抗原阴转或转换的几率大大增加。该疗法与以往药物最大不同之处就是能“唤醒”患者体内免疫细胞，从而为抗病毒治疗创造有利条件，最大限度地抑制或清除乙肝病毒，对转氨酶升高的乙肝患者尤为适用。

Professor Yang introduces,Therapeutic hepatitis b vaccine therapy can be induced in patient blood surface antigen concentration decline,After discontinuation of prevention with three years,These patients occurred surface antigen Yin turn or convert chance to increase greatly.The therapy and drug before the biggest difference is the can"Wake up"In patients with immune cells,So as to create favorable conditions for antiviral treatment,Maximum inhibition or clear hepatitis b virus,To second liver patient of transaminase eleations is particularly applicable.

　　不过，专家也称，治疗性乙肝疫苗疗法暂不能取代抗病毒药物，该疗法经卫生部批准作为第三类医疗技术在有条件的三甲医疗机构逐步推广。(完)

but,Experts also say,Therapeutic hepatitis b vaccine therapy temporary can't take place of antiviral drugs,The treatment after approved by the public health ministry as a third class medical technology in the top three conditional medical institution promotes gradually.(finish)