瑞典和芬兰研究人员最新研究发现，基因组区域中一种特定核苷酸变异与大肠癌和前列腺癌患病风险有着重要联系，是引发这两种癌症的“开关”。

The Swedish and Finnish researchers study has found,Genome area a kind of specific nucleotide mutation and large intestine cancer and prostate cancer risk are important link,Is the leading cause of these two kinds of cancer"switch".

　　瑞典卡罗林斯卡医学院和芬兰赫尔辛基大学研究人员在新一期美国《科学》杂志上报告说，他们在动物实验中移除了实验鼠体内存在核苷酸变异风险的基因区域“Myc335”，结果发现，其体内“MYC”的基因表达受到强烈抑制，而老鼠的健康状况并未受到负面影响。此前研究发现，“MYC”的过度表达与癌变有重要关联，许多癌症患者体内的MYC基因都过度活跃。

The karolinska institute named the winners and researchers at the university of Helsinki, Finland in a new phase of the United States[science]Report in the journal said,They in animal experiments removed some laboratory mice exist nucleotide mutation genetic risk area"Myc335",The results showed that,The body"MYC"Gene expression by strong inhibition,And mice health are not affected by the negative effects.Previous research found that,"MYC"Excessive expression and canceration has important relation,Many cancer patients body MYC genes have overactivity.

　　研究人员说，虽然研究表明这段基因组区域的特定核苷酸变异只将患癌风险增加了20%，但和其他已知的遗传变异或基因突变相比，它与遗传性癌症的基因联系更为密切。

The researchers say,Although research shows that this period of genome area specific nucleotide mutation will only a 20% increase in the risk of developing cancer,But and other known genetic variation or compared gene mutation,It and hereditary cancer gene relation more closely.

　　研究人员认为，新发现有助于未来的癌症防治，但距离相应药物的问世还需要很多年的深入研究。（记者和苗 孙征）

Researchers believe that,New findings help to the future of cancer control and prevention,But distance corresponding drugs for many years was still need further research.(Journalists and SunZheng seedlings)