中新社上海12月8日电(记者 邹瑞玥)在8日于此间举行的第九届“华为杯”全国研究生数学建模竞赛上传出消息，来自上海交通大学的欧阳廷婷、武发明和丰子灏利用数学算法，成功解决了基因识别难题。

China news agency on December 8, Shanghai(Reporter ZouRuiYue)In 8, held here in the ninth"Huawei cup"The national postgraduate in the mathematical contest in modeling came news,From Shanghai jiaotong university OuYangTingTing/Wu invention HeFeng son Hao using mathematical algorithm,Successfully resolved the gene identification problem.

　　每个人的长相、身体状况之所以各不相同，就是因为DNA的存在。其中带有遗传信息的DNA片段称为基因，控制着生物的性状。就好像天然金沙掩藏在大量淤泥里一样，在基因片段中存在着“黄金”外显子与“淤泥”内含子，只有外显子上存有遗传信息，而内含子只是冗余信息。所以，去除多余的内含子，把有用的外显子找到，就是欧阳廷婷团队要解决的问题。这一问题是当前生物信息学最基础、最首要的难题。

Each person's face/Physical condition is different,Is because of the presence of DNA.With genetic information of segment of DNA called genes,Control the biological character.Like natural sands hidden in a large number of silt in,In gene fragment there"gold"Exon and"silt"introns,Only exon have genetic information,And introns just redundant information.so,Remove excess introns,The useful exon find,Is OuYangTingTing team to solve the problem.This problem is the most basic current bioinformatics/The first problem.

　　欧阳廷婷团队介绍，他们的“淘金术”原理在于两大法宝：基因频率变化规律与数学算法原理。在基因的运动过程中，会体现出一定频率变化规律，其中最显著的特征之一就是频谱3-周期性，即基因在三个子序列上分布的“非均衡性”，从不均匀的排布上可以看出一些外显子的端倪，对准确定位“黄金”起着举足轻重的作用。

OuYangTingTing team is introduced,their"Panning technique"Principle lies in the two big magic weapon:Gene frequency change rule and mathematical algorithm principle.In the movement of the gene in the process,Will reflect a certain frequency change rule,One of the most significant feature of spectrum is 3 - periodic,Namely gene in three son sequence on the distribution"unbalanced",Never even configuration can be found in some exon of the clue,For accurate positioning"gold"Play a decisive role.

　　大概确定了“黄金”的范围后，就要用信号处理和数学分析的手段处理DNA序列，并建立数学模型。欧阳廷婷团队综合前人的算法，加以提升，设计出了一套精确度更高的基因编码区域识别算法。这一算法将尽量多的真实外显子识别出来，同时尽量少地将内含子错误识别为外显子，也就是最大限度找到“黄金”。欧阳廷婷团队借此获得了大赛一等奖。(完)

It determines the"gold"After the scope of,You'll have to use the signal processing and mathematical analysis method processing DNA sequence,And the mathematical model is established.OuYangTingTing team comprehensive previous algorithm,To improve,Has designed a higher accuracy in the genes that code for regional recognition algorithm.This algorithm will try to many real exon identified,At the same time as far as possible the introns error identification for exon,The maximum is found"gold".This OuYangTingTing team won the first prize in the contest.(finish)